Septic encephalopathy
Septic encephalopathy is brain dysfunction mediated by the septic inflammatory response, independent of other co-existent causes such as liver or renal dysfunction
Septic encephalopathy is brain dysfunction mediated by the septic inflammatory response, independent of other co-existent causes such as liver or renal dysfunction
C. H. Joseph Chang (1929 - 2017) was an American radiologist. Chang sign (CXR finding in pulmonary embolus) decribed in 1965
Transjugular Intrahepatic Portosystemic Shunt Procedure (TIPS) involves accessing the internal jugular vein and IVC to place a stent between the hepatic and portal veins using a needle
Carbon monoxide (CO) is a colourless, odourless gas produced by incomplete combustion of carbonaceous material. CO poisoning may be acute or chronic
Aeromedical Transport of the Critically Ill; risks of transport has to be weighted up against the benefit offered by facility
Transferring the Critically Ill: key principle is that the standard of care should not decrease during or after retrieval of a critically ill patient
Rhabdomyolysis is the breakdown of skeletal muscle fibres with leakage of potentially toxic intracellular contents into the systemic circulation, characterised by elevated plasma creatine kinase, myoglobinuria and risk of renal impairment
FEAST = Fluid Expansion As Supportive Therapy. Trial was a landmark study investigating the effects of fluid boluses in the resuscitation of febrile children with evidence of poor perfusion
Bone R.C. et al (1987) “A controlled clinical trial of high dose methylprednisolone in the treatment of severe sepsis and septic shock” NEJM, 317:653-658 PMID 3306374 RCT n = 382 with sepsis and organ dysfunction methylprednisolone (30mg/kg) vs placebo-> no…
Smoke is a complicated heterogeneous mixture of potentially toxic gases, chemical fumes, asphyxiants and particulate debris. Smoke inhalation is commonly seen in patients with burns as a result of fire; it is associated with high morbidity and mortality
Diabetes insipidus (DI) is a condition caused by loss of the effect of antidiuretic hormone on the collecting ducts of the kidneys, resulting in loss of free water.
A 'volume-targeted' approach to the management of TBI developed by a Swedish group (not ABBA), based on physiological volume regulation of the intracranial compartments. The Lund concept contradicts the prevailing strategem of titrating CPP to match ICP in TBI