Category Medical Specialty
CCC Critical Care compendium 340

Septic encephalopathy

Septic encephalopathy is brain dysfunction mediated by the septic inflammatory response, independent of other co-existent causes such as liver or renal dysfunction

C. H. Joseph Chang (1929 - 2017) 340

C. H. Joseph Chang

C. H. Joseph Chang (1929 - 2017) was an American radiologist. Chang sign (CXR finding in pulmonary embolus) decribed in 1965

CCC Critical Care compendium 340

Rhabdomyolysis CCC

Rhabdomyolysis is the breakdown of skeletal muscle fibres with leakage of potentially toxic intracellular contents into the systemic circulation, characterised by elevated plasma creatine kinase, myoglobinuria and risk of renal impairment

CCC Critical Care compendium 340

Steroids and Septic Shock Literature Summaries

Bone R.C. et al (1987) “A controlled clinical trial of high dose methylprednisolone in the treatment of severe sepsis and septic shock” NEJM, 317:653-658 PMID 3306374 RCT n = 382 with sepsis and organ dysfunction methylprednisolone (30mg/kg) vs placebo-> no…

CCC Critical Care compendium 340

Smoke inhalation

Smoke is a complicated heterogeneous mixture of potentially toxic gases, chemical fumes, asphyxiants and particulate debris. Smoke inhalation is commonly seen in patients with burns as a result of fire; it is associated with high morbidity and mortality

CCC Critical Care compendium 340

Central Diabetes Insipidus

Diabetes insipidus (DI) is a condition caused by loss of the effect of antidiuretic hormone on the collecting ducts of the kidneys, resulting in loss of free water.

CCC Critical Care compendium 340

Lund Concept for Traumatic Brain injury

A 'volume-targeted' approach to the management of TBI developed by a Swedish group (not ABBA), based on physiological volume regulation of the intracranial compartments. The Lund concept contradicts the prevailing strategem of titrating CPP to match ICP in TBI