James Sanders
James Sanders (1777-1843) was a Scottish physician
Overview
Eponym
Biography
- Born 1777
- 1802 – member of the Royal Medical Society of Edinburgh
- Father of William Rutherford Sanders (1828-1881)
- Died 1843
Medical Eponyms
Sanders sign (1823)
The undulatory character of the cardiac impulse in the epigastric region, indicative of adherent pericardium (l’adhérence du péricarde). Specifically the presence of a depression occurring under the left ribs and in the epigastrium during systole in patients with adherent pericardium.
Pendant la contraction simultanée des ventricules, le cœur devient plus court, plus rond dans sa surface, il se rétrécit pour , chasser le sang, sa pointe s’élève en avant vers la cinquième côte et doit entraîner actuellement en haut la partie inférieure du péricarde, avec le diaphragme et tout ce qui lui est adhérent. En même temps se dessine donc l’enfoncement sous les côtes gauches de la région supérieure du ventre.
…pendant la contraction simultanée des deux oreillettes, les ventricules se relâchent, s’étendent pour recevoir le sang, la pointe du cœur se meut subitement en bas, et, n’étant pas dans un espace libre, communique actuellement au péricarde adhérent, au diaphragme, et aux autres parties, le choc, qui est sensible à l’extérieur par une petite élévation qui se dessine dans le même endroit où peu auparavant s’était formée la concavité, et qui s’étend pourtant un peu plus bas. Rigoureusement parlant, l’enfoncement précède le choc, puisque la contraction des oreillettes est le commencement de l’action du cœur.
C’est un mouvement perpétuel d’une très-forte ondulation, se montrant plus bas que celle qu’on sent naturellement dans la région du cœur.
…il existe un signe mécanique, produit toujours par la même et unique cause, signe qui ne trompera jamais, qui fera reconnaître très facilement l’adhérence du péricarde, lors même qu’elle sera compliquée avec d’autres maladies du cœur ou de la poitrine.
During the simultaneous contraction of the ventricles, the heart becomes shorter, rounder on its surface, it narrows to expel the blood. Its apex rises forward toward the fifth rib, causing the lower part of the pericardium to rise with the diaphragm and all that is adherent to it. At the same time a depression under the left ribs of the superior abdominal region is formed.
…during the simultaneous contraction of the two atria, the ventricles relax, dilate to receive the blood, the apex of the heart moves suddenly downwards, and, not having a free space to move in, communicates to the adherent pericardium, the diaphragm, and to the other parts, the shock, which becomes sensible to the outside by a small elevation which is outlined in the same place where the depression had formerly been, and which however extends a little lower. Strictly speaking, the depression precedes the shock, since the contraction of the atria is the beginning of the action of the heart.
It is a perpetual movement of a very strong undulation, showing itself lower than that which one naturally feels in the region of the heart.
…it is a sign which will never deceive, which will enable us to very easily recognize the adhesion of the pericardium, even when it is complicated with other diseases of the heart or chest.
Controversy…not many people agreed
Laënnec acknowledged Sanders, Kreysig and Heim in his book Traité de l’auscultation médiate et des maladies des poumons et du cœur, but was unable to replicate the sign in any of his patients
I have understood that an English physician, Dr. Sanders, has announced as an infallible sign of the adhesion of the pericardium to the heart, the existence of a hollow, during each systole of the organ, in the epigastrium, immediately below the left false ribs. Kreysig attributes the same remark (vol. ii. p. 623) to Dr. Heim of Berlin. During the last two years, I have sought in vain to verify this observation among all my patients who presented any disorder of the circulation; and in none of them have I found the epigastric depression, although several had this very adhesion of the pericardium.
Laënnec 1832 [English translation 1837: 732]
James Hope (1801-1841) was equally as dismissive as he proposed his own sign for adhesive pericarditis
These signs have generally been considered very obscure. Dr. Sanders believed that he had discovered one of a positive nature in a dimple or retraction taking place, as he states, during the ventricular systole, in the epigastrium immediately below the left false ribs. I have searched for this attentively in several cases of adhesion, but have not been able to detect it in any degree which could constitute a sign. Laennec, who was equally unsuccessful, thinks that it could not take place unless the stomach, by adhering both to the diaphragm and the abdominal parietes, formed the medium of retraction.
James Hope 1832: 129
Jean-Baptiste Bouillaud (1796-1881) references Dr James Sanders, but once again has been unable to observe the sign in adherent pericarditis
M. le docteur Sander(s) a donné comme signe de l’adhérence du péricarde au cœur un signe que je n’ai pas eu l’occasion de constater: “un mouvement perpétuel d’une très forte ondulation se montrant plus bas que celle que l’on sent naturellement dans la région du cœur”
Bouillaud. Traité de nosographie médicale. 1846; I: 416
Doctor Sander(s) gave as a sign of the adherence of the pericardium to the heart a sign that I have not had the opportunity to observe: “a perpetual movement of a very strong undulation showing itself lower than the one we naturally feel in the region of the heart “
Bouillaud. Traité de nosographie médicale. 1846; I: 416
Major Publications
- Sanders J. Treatise on pulmonary consumption, in which a new view of the principles of its treatment is supported by original observations on every period of the disease : to which is added an inquiry proving that the medicinal properties of the digitalis, or fox-glove, are diametrically opposite to what they are believed to be. 1808
- Sanders J. Essai sur la digitale pourprée. 1812
- Sanders J. A comprehensive view of the small pox, cow pox, and chicken pox.. 1813
- Testimonials from James Sanders, M.D. as candidate for Professorship. 1821
- Sanders J. Remarques sur le diagnostic de l’adhérence du péricarde au coeur. Archives générales de médecine 1823; 1: 153-157 [Sanders sign]
- Sanders J. Report of the effects of the acid fumigation tried in Scotland, during the prevalence of the epidemic Cholera. 1833
- Sanders J. Suggestions for the consideration of the College Committee concerning the medical curriculum of the University of Edinburgh. 1833
References
- Laënnec RTH. Signs de la péricardite aiguë. In: Traité de l’auscultation médiate et des maladies des poumons et du cœur. 1832; III: 383
- Laënnec RTH. Pericarditis. In: A treatise on the diseases of the chest, and on mediate auscultation, 1837: 732 [English translation Sir John Forbes]
- Ye F et al. Physical Examination Signs of Inspection and Medical Eponyms in Pericarditis Part I: 1761 to 1852. Erclyes Med J 2019; 41(2): 223–229
Eponym
the person behind the name