CCC Critical Care compendium 340
Risk and Numbers Needed to Treat

Risk is a nebulous term in evidence-based medicine, as it may refer to either relative or absolute risks. Overall, absolute risks are more meaningful and can be converted in 'numbers need to treat' (NNT), which are useful in the clinical setting

CCC Critical Care compendium 340
Case-Control Studies

Case-Control Studies: a type of retrospective observational study; control patients are ‘matched’ using some criteria (age, gender), typically should have no history of the disease of interest and should be representative of the general population

CCC Critical Care Compendium 680
Urate (Uric Acid)

Uric acid is the major end metabolite of purine. Purine found in nucleic acid and exogenous sources; Commonly used as marker for gout and pre-eclampsia; Levels do not usually indicate severity of disease

CCC Critical Care compendium 340
Approach to Acute Poisoning

The patient's form a heterogeneous group that requires a systematic approach based on early resuscitation where needed, risk assessment to guide further management and early consideration of the underlying psychosocial issues.