
Fluid bolus therapy
Fluid bolus therapy is widely administered to patients with undifferentiated hypotension and for patients with severe sepsis

Fluid bolus therapy is widely administered to patients with undifferentiated hypotension and for patients with severe sepsis

The fluid challenge (FC) aims at identifying patients in whom fluid administration improves haemodynamics (known as "fluid responsiveness")

Blinding and allocation concealment are used in Randomised control trials (RCTs) to reduce systematic bias

An adaptive clinical trial involves a study design in which key characteristics are adjusted while enrollment in the trial is ongoing using prospectively defined decision rules and in response to information arising from the data accumulating in the trial

Chi-square Test is used to compare categorical data; often displayed in contingency table with rows (x) and columns (y)

Obesity has multiple pathophysiological effects and leads to numerous multi-system complications

Bariatric Patient Hot Case

Reviewed and revised 24 May 2014 OVERVIEW MECHANISM OF ACTION TOXICOKINETICS RISK ASSESSMENT CLINICAL FEATURES Effects include: Complications INVESTIGATIONS (Guided by clinical assessment) Laboratory tests MANAGEMENT Resuscitation Supportive care and monitoring Decontamination Disposition References and Links Journal articles

Renal replacement therapy: Fluid Management

Enhanced elimination techniques serve to increase the rate of removal of an agent from the body with the aim of reducing the severity and duration of clinical intoxication.

Ethanol (ethyl alcohol) is an aliphatic alcohol, C2H5OH. The primary effect of ethanol is CNS depression, which is additive with other CNS depressants

High-dose Insulin Euglycaemic Therapy (HIET) is primarily used in the therapy of severe calcium channel blocker toxicity. HIET can also be used for severe beta blocker toxicity and potentially other toxicities/ presentations requiring inotropic support