Melioidosis – Lab without walls
Melioidosis is a fascinating disease, with a distinct geography, a wide range of clinical presentations and a complex pathogenesis.
Category Infectious Disease
Melioidosis a disease of surprises
Melioidosis Burkholderia pseudomallei is a fascinating disease, with a distinct geography, a wide range of clinical presentations and a complex pathogenesis.
Ebola, the Perfect Political Pathogen
If we want to control ebola, we must act rationally and follow the advice of experts and not cynical reactionaries.
Antibiotics: Preserve the miracle?
The placebo effect is well-known in modern medicine. Unfortunately, the most effective medicines we’ve ever discovered are more often used as placebos rather than cures. What are these medicines? Antibiotics. They’ve added 20 years to the average human life expectancy,…
Rosenbach disease
Description What is the actual eponymous medical sign/syndrome/repair/classification… History 1873 – Tilbury Fox (1836-1879) first to describe what is now generally designated as erysipeloid. In 1873 Fox briefly described two instances of an eruption clinically conforming with that disease. 1873…
Losing the War on Resistant Gram Negatives
Extended spectrum beta-lactamases (ESBLs) have been a challenge to antimicrobial therapy since the 1980s and still continue to be...
The Bordetella pertussis epidemic
The current Bordetella pertussis epidemic began in 2008. The peak of the outbreak was reached in 2009 with 35,000 cases (156 per 100,000 population) with the most affected age group being the 5-9 year old cohort. Though immunisation is above 90%…
Man catches gizmonotic virus
In the future infectious diseases specialists will not only have human infections and zoonoses to deal with, but gizmonotic diseases (like computer viruses) as well.
Malaria vaccine
The malaria disease is caused by a Plasmodium protozoal parasite, post proboscis penetration by an infected Anopheles mosquito. Here we discuss Malaria vaccine
Leptospirosis
Leptospirosis is an infection caused by the spirochaete genus of Leptospira. Severe forms may result in critical illness, including Weil disease and severe pulmonary haemorrhage
Haemophagocytic lymphohistiocytosis
Haemophagocytic lymphohistiocytosis (HLH) may be inherited (AR; 5 subtypes, aka familial HLH) or acquired; may mimic severe sepsis, consider in apparent sepsis without source
Antibacterial Resistance
Antibacterial Resistance: Natural Resistance – they do not possess the molecular target of the drug or are impermeable to it; Acquired resistance – occurs through mutation or the acquisition of new genetic material carried by mobile elements