Myasthenia Gravis
Myasthenia Gravis: autoimmune disruption of post-synaptic acetylcholine receptors at NMJ; up to 80% of functional receptors loss; typically young woman; may have thymus hyperplasia; prevalence = 14.2 cases per 100,000
Category Neurology
Myopathy versus Neuropathy
Myopathy versus Neuropathy
Neurology Literature Summaries
Neurology Literature Summaries
Non-Convulsive Status Epilepticus (NCSE)
Non-Convulsive Status Epilepticus (NCSE) is a persistent change in the level of consciousness, behaviour, autonomic function, and sensorium from baseline associated with continuous epileptiform EEG changes, but without major motor signs
Long-term cognitive impairment in Critical Illness
Critical illness is associated with a spectrum of neurological failure (largely under-reported), including polyneuropathy, encephalopathy and long-term cognitive impairment after critical illness (LTCI-CI)
Septic encephalopathy
Septic encephalopathy is brain dysfunction mediated by the septic inflammatory response, independent of other co-existent causes such as liver or renal dysfunction
Encephalitis
Encephalitis an acute encephalopathy due to an inflammatory cause
Underlying causes are numerous and may be infectious or non-infectious, many of which lack effective therapies
Stroke Thrombolysis
Stroke Thrombolysis: thrombolysis for acute ischaemic stroke is a controversial intervention; it is supported by a number of guidelines and in general is viewed favourably by the neurological community
Tenecteplase (TNK-tPA)
Tenecteplase is a tissue plasminogen activator used as a thrombolytic medication in: Acute Ischaemic Strokes, Acute Myocardial Infarction, PE
A Spider called Willis
A ferocious spider lives in the brain. His name is Willis!
Sidney Weinstein
Sidney Weinstein (1922 - 2010) was and American neuroscientist and neuropsychologist. Semmes-Weinstein monofilament test and the Weinstein Enhanced Sensory Test
Adie syndrome
Holmes-Adie syndrome (aka Adie syndrome) affects the autonomic nervous system. Patients present with the pupil of one eye being larger and only slowly constricts in bright light (tonic pupil). There is also absence of deep tendon reflexes, usually the Achilles tendon.