Antibiotic Dosing in Renal Replacement Therapy
Little published data to guide dosing of antibiotics in RRT and the critically ill. therefore we must use first principles and utilize therapeutic drug monitoring if available.
Category Medical Specialty
Cerebral Perfusion Pressure in TBI
Cerebral Perfusion Pressure (CPP) in Traumatic brain injury (TBI). Cerebral Perfusion Pressure (CPP) = MAP – ICP or CVP (whichever is highest)
Bronchiolitis
Goals: resuscitation severity and stability of disease assessment of possible differentials including cardiac disease, influenzae, pertussis stabilisation and possible transfer to neonatal/SCBU if required
Drowning
Drowning is the process of experiencing respiratory impairment from submersion/immersion in liquid (WHO 2002 definition)
drowning can be due to — submersion (the airway goes below the level of the surface of the liquid) or — immersion (a liquid is splashed across a person’s face, e.g water-boarding)
Anaphylaxis
Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway (pharyngeal or laryngeal edema) and/or breathing (bronchospasm and tachypnea) and/or circulation (hypotension and tachycardia) problems usually associated with skin and mucosal changes
Resuscitation Team Leader
The roles and priorities in a cardiac arrest situation is dependent on: the environment where arrest takes place; the nature of the cardiac arrest, ; and the skill mix of the people in the immediate environment
Immediate Post-ROSC Management
A team-based approach to the management of the post-ROSC patient focuses on initiation of therapeutic hypothermia, treatment of the underlying cause with transfer to the cath lab where appropriate, and management of the post-cardiac arrest syndrome.
Deresuscitation and Positive Fluid Balance
Deresuscitation specifically refers to 'Late Goal Directed Fluid Removal (LGFR)', which involves "aggressive and active fluid removal by means of diuretics and renal replacement therapy with net ultrafiltration" (Malbrain et al, 2014)
Systolic pressure variation
Systolic Pressure Variation and Stroke Volume Variation between spontaneous breathing and mechanical ventilation
Inotropes, vasopressors and other vasoactive agents
Vasoactive agents include the following: inotropes; vasopressors; inodilators and some that don't fit like dopamine...
Chronic Graft Versus Host Disease
Chronic Graft vs Host Disease is organ dysfunction occurring > 100 days post transplantation; distinct clinical syndrome from acute GVHD; pathophysiology poorly understood
Encephalitis
Encephalitis an acute encephalopathy due to an inflammatory cause
Underlying causes are numerous and may be infectious or non-infectious, many of which lack effective therapies