Ventriculitis
Bacterial ventriculitis (BV) is inflammation of the ventricular drainage system, usually due to bacterial infection of the cerebrospinal fluid (CSF)
Category Medical Specialty
Vasospasm in Subarachnoid Haemorrhage
Vasospasm in SAH: vasospasm = dynamic narrowing of vessels due to a radiological diagnosis; delayed neurological deterioration (DND) is clinically detected neurological deterioration after stabilisation not due to re-bleeding, may be due to multiple other causes; delayed cerebral ischaemia (DCI) is any neurological deterioration >1 hour that presumed due to ischemia, and other causes excluded
Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE) = chronic, multi-system disease commonest in young females; wide spread antibodies -> produce tissue damage
Scleroderma
Scleroderma = autoimmune mediated widespread collagenous deposition. Limited form: Calcinosis, Raynauds, Esophageal dysfunction, Sclerodacytaly and Telangiectasia (CREST syndrome)
Polyangiitis – MPA, GPA, EGPA
Polyangiitis - MPA, GPA, EGPA: similar but different diseases; positive Antineutrophil cytopasmic antibiodies (ANCA); renal histology (focal necrotizing, pauci-immune glomerulonephritis)
John Birkett
John Birkett (1815-1904) was an English general surgeon.
Bispectral Index (BIS) Monitoring
Bispectral Index (BIS) Monitoring: BIS monitor was developed by Aspect Medical Systems; BIS = bispectral index; other 'depth of anaesthesia' monitors exist (e.g. Entropy)
Isoniazid toxicity
Isoniazid toxicity, like other hydrazines, primarily cause life-threatening seizures and lactic acidosis through depletion of vitamin B6. The antidote is pyridoxine
Acute Fatty Liver of Pregnancy
Acute Fatty Liver of Pregnancy: hepatic dysfunction + microvesicular infiltration of hepatocytes; thought to be a variant of PET; fetal and maternal mortality = 20%
Amniotic Fluid Embolism (AFE)
Amniotic Fluid Embolism (AFE): diagnosis of exclusion; amniotic in maternal circulation not always pathognomonic; 1:25,000 live births
Burns and Pregnancy
Burns and Pregnancy: at risk of premature labour due to high levels of circulating prostaglandins; fluid replacement must cater for increased circulating volume
Cardiogenic Shock and Late Pregnancy
Cardiogenic Shock and Late Pregnancy: Two patients; High mortality; Planned delivery; Diagnose and treat cause