CCC Update 002

I promised to provide an update on what’s new and what has changed in the LITFL CCC from time to time. Then I held back because it didn’t make for a riveting read by any stretch. However, now that it turns out that some people are actually using the CCC I’ve started to receive a few requests on how to track changes. Hence, there is a need for occasional updates after all.

So here’s what’s new in the CCC (in fairly random order):

Adaptive Trial Designs

  • are traditional RCTs the way forward? Will there ever be a valid trial in critical care with a positive result? Maybe adaptive trial designs will be the answer.

TTM is out and I’ve had to do a fair bit of revising and reviewing as a result. All of these CCC entries have been updated:

Ammonia and hyperammonaemia

  • added a great free full text reference

Obesity and Trauma

  • do you know the injury patterns, complicating factors and outcomes?

Antibiotic timing

  • how important are early antibiotics in severe sepsis, meningitis and pneumonia?

Quorum sensing

  • wow, turns out bacteria can communicate! This may be an important mechanism for bacterial invasion in disease states

Stenotrophomonas multophilia

  • this bug is on the rise in ICU, and we need to know about it

That’s it ’til the next update. Remember to leave comments, point out errors and make suggestions on as many pages as possible!

CCC 700 6

Critical Care


Chris is an Intensivist and ECMO specialist at the Alfred ICU in Melbourne. He is also a Clinical Adjunct Associate Professor at Monash University. He is a co-founder of the Australia and New Zealand Clinician Educator Network (ANZCEN) and is the Lead for the ANZCEN Clinician Educator Incubator programme. He is on the Board of Directors for the Intensive Care Foundation and is a First Part Examiner for the College of Intensive Care Medicine. He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives.

After finishing his medical degree at the University of Auckland, he continued post-graduate training in New Zealand as well as Australia’s Northern Territory, Perth and Melbourne. He has completed fellowship training in both intensive care medicine and emergency medicine, as well as post-graduate training in biochemistry, clinical toxicology, clinical epidemiology, and health professional education.

He is actively involved in in using translational simulation to improve patient care and the design of processes and systems at Alfred Health. He coordinates the Alfred ICU’s education and simulation programmes and runs the unit’s education website, INTENSIVE.  He created the ‘Critically Ill Airway’ course and teaches on numerous courses around the world. He is one of the founders of the FOAM movement (Free Open-Access Medical education) and is co-creator of litfl.com, the RAGE podcast, the Resuscitology course, and the SMACC conference.

His one great achievement is being the father of three amazing children.

On Twitter, he is @precordialthump.

| INTENSIVE | RAGE | Resuscitology | SMACC

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