Edward Janeway

Edward Gamaliel Janeway (1841 – 1911) was an American physician and pathologist.

Remembered for his description of Janeway lesions in 1899 as a distinctive painless dermatological manifestation seen in some cases of infective endocarditis

  • Born August 31, 1841 in New Jersey
  • 1860 – A.B. Rutgers
  • 1861 – Medical cadet in the U.S. Army Hospital in Newark, New Jersey
  • 1864 – Graduated in medicine, College of Physicians and Surgeons in New York City
  • 1864 – Intern at the smallpox hospital, Blackwell’s Island
  • 1866 – 1872 Pathologist and curator at Bellevue Hospital in New York
  • Died February 10, 1911

Medical Eponyms

Janeway lesion (1899)

Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are indicative of infective endocarditis. To be differentiated from painful Osler nodes.

Janeway lesions @Toaster_Pastry
Janeway lesions via @Toaster_Pastry

In trying to determine whether a given case is more probably due to endocarditis or to another malignant process I have found that attention to the position of the hemorrhages is at times very helpful. Several times I have noted numerous small hemorrhages with slight nodular character in the palms of the hand and soles of the feet, when possibly the arms and legs had but a scanty crop in malignant endocarditis, whereas this has not been my experience with processes likely to be mistaken for it.

Janeway, 1899

Major Publications


Doctor in Australia. Keen interest in internal medicine, medical education, and medical history.

BA MA (Oxon) MBChB (Edin) FACEM FFSEM. Emergency physician, Sir Charles Gairdner Hospital.  Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

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