A 22 year old man has just returned from a surfing trip to Timor. While away he developed a fever, headache and generalised aches and pains. The fever settled for a day or two but has now returned and he has developed a rash. The aches and pains continue unabated. He feels miserable.
Mirtazapine is a novel tetracyclic antidepressant, in overdose it frequently has a benign course with mild CNS depression and tachycardia.
SNRIs or Selective serotonin and noradrenaline reuptake inhibitors are mainly in the form of venlafaxine and desvenlafaxine. Venlafaxine in overdose can be potentially life threatening, causing seizures and cardiotoxicity.
SSRIs or Selective serotonin reuptake inhibitors are common in overdose and usually follow a benign course. Serotonin toxicity occurs in a minority but is more common with co-ingestant agents with serotonergic action
This is your one stop page for TCA overdose. Find out how to manage the acute overdose and the potential complications. We have also covered the basic TCA pharmacology and a tutorial about sodium channel blockade and the ECG, find out why the QRS will widen.
The non-sedating antihistamines include cetirizine, desloratadine, fexofenadine, levocetirizine and loratadine. In overdose they cause mild CNS depression, in therapeutic and supra therapeutic doses they have been associated with QT prolongation.
The sedating antihistamines include brompheniramine, chlorpheniramine, cyproheptadine, dexchlorpheniramine, dimenhydrinate, diphenhydramine, doxylamine, pheniramine and promethazine
10yr old boy who presented with mild wheeze and shortness of breath. Vitals signs: BP 105/60 RR 20 T 36.4 Sats 99%. Describe and interpret this ECG. LITFL Top 100 ECG
Black Snake antivenom (equine IgG Fab) can be used to treat envenomation from the black snakes in Australia and Papua New Guinea, these include the mulga snake, Butler's mulga snake, Collett's snake, Papuan black snake, red-bellied black snake and the blue-bellied black snake
Brown Snake antivenom (equine IgG Fab) can be used to treat envenomation from the brown snakes in Australia, these include the eastern and western brown snake (gwardar), dugite and other Pseudonaja species
Death Adder antivenom (equine IgG Fab) can be used to treat envenomation from the death adder in Australia and Papua New Guinea.
Tiger Snake antivenom (equine IgG Fab) can be used to treat envenomation from the Tiger snakes in Australia, these include the Common and western Tiger snake, Stephen's banded snake, pale-headed snake, broad-headed snake, rough-scaled snake, copperhead snake and the small-eyed snake