Research and Reviews in the Fastlane 340
Time to publish then filter?

I came across this post while getting up to speed with Critical Insight, a UK-based online blog-come-journal club. It had a link to a recent BMJ editorial by David Schriger and Douglas Altman — you may remember David Schriger from…

Book Review LITFL 340
Clinical Neurology a primer

Clinical neurology a primer is written by leading Australian neurology Associate Professor Peter Gates. This book is the ultimate guide to neurology for people like me – who don’t understand it, but need to know it! Available in kindle edition…

Stu Marshall on Airway Strategies

Stuart Marshall is an anaesthetist with a PhD in Human Factors and is the Clinical Director of Simulation Education at The Alfred (based at the Australian Centre for Health Innovation). In this FOAM video, created for the Critically Ill Airway…

Conferences
The World at War!

That’s right, SMACC SimWars is turning into a global conflict. Hot on the heels of EMCrit’s Scott Weingart announcing himself to be one of SMACC’s elite SimWars judges (and confessing his delight in the sadistic elements of his co-creation), the…

UCEM-logo 340
Not Backwards in going Backwards

The newly formed Southern Hemisphere Information Technology '4 brains' group have covertly implemented a series of strategies within Australian hospitals which they are confident will coagulate productivity to a state of suppuration.

Toxicology-Library-Antidote-340-256
Vitamin K

An essential co-factor in the synthesis of clotting factors II, VII, IX and X. It is used for the reversal of coumadin-induced coagulopathy.

Toxicology-Library-Antidote-340-256
Sugammadex

Sugammadex is used for reversal of the amino steroid neuromuscular blocking drugs rocuronium, vecuronium and pancuronium. It does not work on non-amino steroid neuromuscular blocking drugs (atracurium, cisatracurium and suxamethonium).

Toxicology-Library-Antidote-340-256
Succimer

Succimer (DMSA) is an orally active metal chelator is used to treat heavy metal poisoning. In adults Succimer is used for symptomatic lead poisoning or in patients who are asymptomatic with levels >60 micrograms/dL (>2.9 micro mol/L). In paediatrics it is used for symptomatic lead poisoning or in patients who are asymptomatic with levels >45 micrograms/dL (>2.17 micro mol/L).

Toxicology-Library-Antidote-340-256
Sodium thiosulphate

Sodium Thiosulfate enhances the endogenous cyanide detoxification capacity of the body. It is suitable to use alone in the treatment of mild to moderately severe cases of cyanide poisoning but should be used in conjunction with other antidotes such as hydroxocobalamin in severe cyanide toxicity.

Toxicology-Library-Antidote-340-256
Sodium Calcium edetate

Sodium Calcium Edetate (EDTA) is an intravenous heavy metal chelating agent. EDTA is primarily used in the treatment of severe lead poisoning with or without lead encephalopathy or an asymptomatic/mildly symptomatic patient with a serum lead level >70 microgram/dL (3.38 micro mol/L).

Toxicology-Library-Antidote-340-256
Sodium Bicarbonate

Hyperosmolar sodium bicarbonate solutions are widely used in clinical toxicology both as an antidote to drugs that impair fast sodium channel function and as an alkalinising agent to manipulate drug distribution and excretion (salicylate and phenobarbitone). It is also used in profound metabolic acidosis with cyanide, isoniazid and toxic alcohol toxicity.