Question The following list refers to classes of oral anticoagulation regimens for use in chronic atrial fibrillation: i. Antiplatelet agents ii. Vitamin K antagonists iii. Antithrombin agents iv. Anti Xa agents a) Give an example of a drug for each…
The Alvarado score is a 10 point score for predicting acute appendicitis (mnemonic MANTRELS). Alfredo Alvarado in 1986
Sidney Farber (1903-1973) was an American pediatric pathologist. Farber disease (1952) autosomal-recessive, lysosomal storage disorder caused by acid ceramidase deficiency and associated with distinct clinical phenotypes
Theophylline CCC
Edwin Sterling Munson (1870-1958) was an American ophthalmologist.Munson sign, a V-shaped indentation of the lower eyelid when the gaze is directed downwards, an indication that is characteristic of advanced keratoconus.
LITFL contributor Aaron Sparshott (@IVline) has made a nice little video presentation on the ins and outs of Pecha Kucha, and how to make an online PK SMACCtalk. It is perfect for all the SMACCheads out there needing that extra…
1933 – Kartagener described the syndrome of situs inversus, chronic rhinosinusitis, and chronic bronchitis with bronchiectasis
High-dose insulin therapy is a novel therapeutic intervention that produces a significant inotropic response in severe calcium channel blocker (CCB) overdose and occasionally in beta blocker overdose.
Funtabulously Frivolous Friday Five 156 - Just when you thought your brain could unwind on a Friday, some medical trivia FFFF.
Idarucizumab is the antidote to dabigatran. Perhaps the hardest thing about it is saying its name. Eye-da-roo-ciz-oo-mab or praxbind until to comes off label. It is a humanised monoclonal antibody fragment (Fab) that binds to dabigatran with very high affinity (340x fold more than dabigatran binds to thrombin).
Hydroxocobalamin is a vitamin B12 (cyanocobalamin) precursor. In high doses, it is an effective chelator of cyanide. It is also the preferred antidote to cyanide poisoning due to its low side effect profile, thus if given to a patient without cyanide poisoning there is low risk of an adverse outcome
Symptomatic hypoglycaemia resulting from toxic exposures must be immediately corrected by administration of glucose. In all but the mildest of cases this is achieved with an intravenous bolus of hypertonic glucose solution