CCC Critical Care compendium 340
Calcium Metabolism

Calcium: highly regulated cation
involved in: cell death, duration and strength of cardiac muscle contraction, muscle contraction in blood vessels, airways and uterus, coagulation, bone metabolism, neurotransmitter and hormone release…

CCC Critical Care compendium 340
Urinary Electrolytes

Urinary Electrolytes: used in the diagnosis of a number of electrolyte disturbances in ICU (especially when intake of electrolytes is known and relatively controlled)

CCC Critical Care compendium 340
SIADH

Syndrome Of Inappropriate ADH secretion (SIADH) is hyponatraemia due to an increase in concentration of ADH inappropriate to the current osmotic or volume status. The differential diagnosis includes ADH analogues

CCC Critical Care compendium 340
Hypophosphataemia

Hypophosphataemia: Phosphate - important intracellular anion; 85% is stored in bone as hydroxyapapitie crystals, 14% in soft tissues, 1% in blood

CCC Critical Care compendium 340
Hypernatraemia

Hypernatraemia can be caused by a number of critical illnesses: water depletion (decreased intake, hypotonic fluid loss – renal/non-renal); solute excess (Na+ or other)

CCC Critical Care compendium 340
Hypercalcaemia

Ca2+ exists in the extracellular plasma two states: (1) free ionized state and (2) bound to other molecules (mostly albumin, rest – beta-globulins, phosphate, citrate)
ionized Ca2+ concentration is inversely related to pH -> an increase in pH results in a decrease in ionized Ca2+