Ethanol Intoxication, Abuse and Dependence
Ethanol (ethyl alcohol) is an aliphatic alcohol, C2H5OH. The primary effect of ethanol is CNS depression, which is additive with other CNS depressants
High-dose Insulin Euglycaemic Therapy
High-dose Insulin Euglycaemic Therapy (HIET) is primarily used in the therapy of severe calcium channel blocker toxicity. HIET can also be used for severe beta blocker toxicity and potentially other toxicities/ presentations requiring inotropic support
CICM SAQ 2015.2 Q28
A 76-year-old female is admitted to the ICU following elective aortic and mitral valve replacement. Trans- oesophageal echo assessment at the end of surgery showed an ejection fraction of 20%. Her preoperative creatinine was 340 μmol/L. Total bypass time was 240 minutes.
CICM SAQ 2015.2 Q26
Question A 27-year-old female presents to the Emergency Department after a collapse at work that was followed by a brief tonic-clonic seizure. She is 30 weeks pregnant with no previous pregnancies or other significant medical history. She currently localises bilaterally…
CICM SAQ 2015.2 Q22
Question A health care worker, recently returned from West Africa, presents to the Emergency Department with fevers, vomiting and diarrhoea. Her vital signs are normal on presentation. Blood tests have not been taken, and venous access has not been established.Your…
CICM SAQ 2015.2 Q17
A 45-year-old male is admitted to the Emergency Department after ingesting an unknown quantity of “headache tablets”. His initial complaints are nausea, vomiting, shortness of breath and tinnitus. Fluid resuscitation has been commenced.
How to conduct a clinical trial
Broad overview of the complicated process of conducting a clinical trial. Conducting a clinical trial can be conceptualised as having 14 key steps
Before-and-after studies
Non-experimental observational study design used to assess the effect of an intervention based on comparison of outcomes prior to its use and afterward
Subgroup Analysis
Subgroup analysis involves assessing an association between an intervention (or other factor) and a subset of the patients that were exposed. Subgroup analysis can be decided upon a priori or performed post hoc
Types of Research Studies
Types of study design arranged by level of evidence, from low to high
Bronchopleural Fistula
Bronchopleural fistula is an unnatural communication between the bronchial tree and pleural space as evidenced by continued leak post-pneumothorax. Can be life-threatening and difficult to manage
Decompression Sickness
Decompression sickness, is a form of decompression illness, where a reduction in ambient pressure ('decompression') leads to de no intravascular and extravascular bubble formation with pathological consequences