Levosimendan vs Dobutamine
COMPARISON EVIDENCE Mebazza, (2007) SURVIVE – Levosimendan vs Dobutamine in patients with acute decompensated heart failure, JAMA References and Links
COMPARISON EVIDENCE Mebazza, (2007) SURVIVE – Levosimendan vs Dobutamine in patients with acute decompensated heart failure, JAMA References and Links
Levosimendan: Calcium sensitizer (novel inotrope, also considered an inodilator like milrinone)
Lignocaine: local anaesthetic and membrane stabilising anti-arrhythmic; binds selectively to refractory Na+ channels -> preferentially when cells are depolarised (ie. in ischaemia)
Linezolid: oxazolidinone; blocks ribosomal function required for translation
Lithium: mood stabiliser; element of the alkali metal group; exact mechanism of action in mania is unknown
Low Molecular Weight Heparin (LMWH): anticoagulant; potentiates the action of antithrombin III on Xa
Pseudocoma is the term used for a patient feigning a comatose state, however it is sometimes also used for conditions like locked-in syndrome where patients may involuntarily appear unconscious but are actually self aware
References and Links
Spinal cord syndromes
Status epilepticus: continuous seizure activity for 5 minutes or more without return of consciousness, or recurrent seizures (2 or more) without an intervening period of neurological recovery
Transverse Myelitis: myelitis is a rare inflammatory condition of spinal cord characterised by pyramidal (motor), sensory, and/or autonomic dysfunction to varying degrees. The term “transverse” originally referred to the clinical finding of a band-like horizontal area of altered sensation usually at the dermatomal level of the lesion within the cord, more recently it is used simply describes the position of the inflammation, that is, across the width of the spinal cord
Watershed infarcts result from severe hypotensive insults. They occur in areas with relatively poor blood supply at the boundaries between territories of cerebral arteries or their branches.