
Ventilation Literature Summaries
Ventilation, summaries of key papers from the ventilation literature: NIV; ARDS; Tracheostomy; Weaning

Ventilation, summaries of key papers from the ventilation literature: NIV; ARDS; Tracheostomy; Weaning

OVERVIEW Pressure versus Time Graph. Information obtained COMMON ABNORMALITIES Normal High Raw High Flow Inadequate inspiratory flow Decreased Lung Compliance Auto PEEP Dynamic Hyperinflation Cardiac oscillations Circuit leaks References and Links

Volume vs time graph: shape determined by flow pattern used in ventilation mode:-> ascending ramp: square wave; -> sinusoidal ramp: sine wave; -> exponential rise: decelerating flow pattern

Flow Volume Loops. provide a graphical analysis of inspiratory and expiratory flow from various inspired lung volumes. Breathing across a pneumotachograph subjects inhale to TLC -> FEC manoeuvre -> rapidly inhale back to TLC.

Volutrauma = complication from mechanical ventilation that may manifest as: extra-alveolar air and/or acute ventilator induced lung injury.

High Frequency Ventilation ventilation with small tidal volumes at high frequencies

OVERVIEW SUMMARY Mucociliary Clearance Optimization Lung Expansion Optimization Ventilation and Oxygenation Optimization Advanced Therapies References and Links

Sedation is the depression of a patient's awareness to the environment and reduction of his or her responsiveness to external stimulation

Intrinsic PEEP is also known as autoPEEP or PEEPi. Intrinsic PEEP occurs when the expiratory time is shorter than the time needed to fully deflate the lungs, preventing the lung and chest wall from reaching an elastic equilibrium point

Determining compliance and resistance within a respiratory system is important during the management of mechanical ventilation.

sigmoid shape of the oxy-Hb dissociation curve results from the allosteric interactions of the globin monomers that make up the haemoglobin tetramer as each one binds O2. Multiple factors can affect the affinity of Hb for oxygen, thus causing the curve to shift to the left (increased oxygen affinity) or to the right (decreased O2 affinity)

Acute Respiratory Distress Syndrome (ARDS) Literature Summaries