Neurological Toxicity of Chemotherapy
Neurological Toxicity of Chemotherapy: Encephalopathy; Cerebellar Syndrome; Myelopathy; Peripheral Neuropathy; Stroke and Venous Thrombosis; SIADH
Category Neurology
Acute Non-Traumatic Weakness
Acute non-traumatic weakness may occur as a result of a wide variety of underlying etiologies, many of which are life-threatening
Anti-NMDA Receptor Encephalitis
Anti-NMDA Receptor Encephalitis is an under-recognised progressive neurological disorder caused by antibodies against NR1-NR2 NMDA receptors; 60% of patients with anti-NMDA receptor encephalitis have the presence of a tumour (most commonly teratoma)
Aseptic Meningitis
Aseptic Meningitis = meningeal inflammation with negative bacterial cultures.
Basilar Artery Occlusion
Basilar Artery Occlusion: the clinical effects will be dependent on: adequacy of collaterals, integrity of the Circle of Willis and the onset of the occlusion; occlusion at the bifurcation will involve the posterior cerebral artery +/- the superior cerebellar artery
GBS vs Myasthenia Gravis vs MND
GBS vs Myasthenia Gravis vs MND
Brain Herniation
Brain herniation is the displacement of part of the brain through an opening or across a separating structure into a region that it does not normally occupy.
Bulbar Dysfunction in ICU
Bulbar Dysfunction in ICU
Cerebral oedema
TYPES Cytotoxic edema Intracellular edema Intact blood brain barrier Loss of grey-white differentiation as it predominantly affects grey matter) suggests stroke or hypoxic encephalopathy “restricted diffusion” pattern on MRI Vasogenic edema Extracellular edema Loss of integrity of blood brain barrier…
Eye Movements in Coma
A simplified approach to spontaneous eye movements in coma
Alteplase (rtPA)
Alteplase is a tissue plasminogen activator used as a thrombolytic medication in: Acute Ischaemic Strokes, Acute Myocardial Infarction and PE
Oculocephalic and oculovestibular reflexes
Oculocephalic and oculovestibular reflexes are primarily used to determine whether a patient's brainstem is intact (e.g. coma or brain death assessment)