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Drugs Causing QT Prolongation

Antipsychotics

  • Chlorpromazine
  • Haloperidol
  • Droperidol
  • Quetiapine
  • Olanzapine
  • Amisulpride
  • Thioridazine

Type IA antiarrhythmics

  • Quinidine
  • Procainamide
  • Disopyramide

Type IC antiarrhythmics

  • Flecainide
  • Encainide

Class III antiarrhythmics

  • Sotalol
  • Amiodarone

Tricyclic antidepressants

  • Amitriptyline
  • Doxepin
  • Imipramine
  • Nortriptyline
  • Desipramine

Other antidepressants

  • Mianserin
  • Citalopram
  • Escitalopram
  • Venlafaxine
  • Bupropion
  • Moclobemide

Antihistamines

  • Diphenhydramine
  • Astemizole
  • Loratidine
  • Terfanadine

Other

  • Chloroquine
  • Hydroxychloroquine
  • Quinine
  • Macrolides: Erythromycin; Clarithromycin

Advanced Reading

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LITFL Further Reading

ECG LIBRARY

Emergency Physician in Prehospital and Retrieval Medicine in Sydney, Australia. He has a passion for ECG interpretation and medical education | ECG Library |

One comment

  1. I realize your list for QTc prolonging medications is not exhaustive, but I really think it should include ondansetron since its a very commonly used agent.

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