Toxicology-Library-Toxicant-Drug-340-256
Calcium channel blocker toxicity

Calcium channel blockers are not all born the same. Some produce severe cardiotoxic effects which in the past has caused significant mortality and others cause severe peripheral vasodilatation

Toxicology-Library-Toxicant-Drug-340-256
Clonidine toxicity

Clonidine has a vast array of uses including anxiety, ADHD, hypertension, withdrawal (opitates, alcohol and smoking), migraines, menopausal flushing, diarrhoea and finally pain. It causes the classic triad of drowsiness, miosis and bradycardia in overdose.

Toxicology-Library-Toxicant-Drug-340-256
Chloroquine and Hydroxychloroquine

Commonly used on holidays in malaria prone destinations, chloroquine and hydroxychloroquine will not be over familiar to the emergency physician. However, it is one of the leading causes of drug overdose in malaria prone countries and also the occasional toddler has managed to consume the grandparents lupus or rheumatoid arthritis medication leading to lethal consequences.

eponym LITFL 340
Lessons from our past

Thanks to Holly Tucker from Wonders and Marvels for re-stimulating my love of medical history. There is a wealth of information hidden in chronicles from the past – with much of it still pertinent to medicine today. Just wanted to…

arcanum veritas LITFL 340
Ever tried smoking?

Perhaps hospitals were a little hasty in becoming "smoke-free" zones - next time I lead a code I might see if anyone volunteers to be the pipe operator for a good old-fashioned tobacco smoke enema...