OVERVIEW Porphyria = group of disorders where patients have a inability to synthesis Hb resulting in an accumulation of precursors oxidised to porphyrins hepatic and erythropoietic varieties 3 hepatic forms that effect are affected by anaesthesia (1) AIP – acute…
Massive venous thrombosis of deep and collateral venous system. Obstruction to outflow causes congestion that can compromise arterial flow
Pancytopaenia
An approach to the patient with persistent bleeding from a venepuncture site
OVERVIEW Lupus Anticoagulants -> result in acquired hypercoagulability due to poorly understood actions ? alteration of the regulation of haemostasis and endothelial cell injury ASSOCIATIONS MANAGEMENT (1) APTT (2) dilute Russell viper venom time (3) silica clotting time(4) kaolin clotting…
Isolated Elevated APTT
Thyroid Storm: life threatening exacerbation of hyperthyroid state with 1 or more organ dysfunction
Pheochromocytoma: paraganglioma -> catecholamine producing tumours; associated with: MEN, von Hippel-Lindau syndrome, neurofibromatosis and familial paragangliomas
Myxoedema Coma: extreme form of hypothyroidism; high mortality
Haemolytic uraemic syndrome (HUS) is a clinically similar condition to TTP; in HUS (unlike TTP): renal failure > neurological symptoms
Reviewed and revised 27 October 2016 OVERVIEW Definition Haemolytic anaemia is anemia due to shortened survival of red blood cells (RBCs) in the circulation Normal RBC lifespan is about 120 days, therefore it is useful to think of hemolytic anemia…
Haematology Literature Summaries