Prognosis After Cardiac Arrest incolves: the underlying cause of cardiac arrest (e.g. overdose vs dilated cardiomyopathy); presence of co-morbidities (e.g. metastatic cancer, dementia); use of targeted temperature management (therapeutic hypothermia); features of the the cardiac arrest and cardiovascular and neurological assessment
Post-cardiac arrest syndrome (aka post-resuscitation syndrome). Occurs after return of spontaneous circulation (ROSC) following cardiorespiratory arrest and involves multiple systems
Reflects a state of whole-body ischaemia and subsequent reperfusion
= immune complex mediated hypersensitivity -> severe erythema multiforme. Separation of the epidermis from the dermis; most authors believe toxic epidermal necrolysis (TEN) and SJS are different ends of the same spectrum of disease
Serious Generalised Skin Disorders: Mnemonic: PTSD-D
CAUSES Meningococcal disease Post-splenectomy pneumococcaemia DIC Rickettsial infections High dose inotropes Endocarditis Venom-induced consumptive coagulopathy (VICC) due to snakebite
The Precautionary Principle (The absence of evidence of risk = a possibility of risk until proven otherwise) and Kehoe Principle (The absence of evidence of risk = Evidence of the absence of risk) reflect different conceptions of risk in the absence of evidence
Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema following a significant central nervous system (CNS) insult
Nitric Oxide: inhalational agent (inhaled nitric oxide, iNO); an inorganic gas - potent, selective pulmonary vasodilator of those areas of the lung being ventilated
Tissue Oxygenation Assessment
Electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring tool that allows real-time imaging of ventilation
EIT has medium spatial resolution and a very high temporal resolution
This page coordinates the reference materials and resources for my talks at the 2013 Annual Scientific Meeting of the College of Intensive Care Medicine. The theme for the conference is 'Down with Dogma — Challenging the Fundamentals of Critical Care'
many more tissue donors available than organ donors; less time critical; early notification allows collection of blood specimens for nucleic acid testing and screening for viral infections; more exclusion criteria (may require full post-mortem to exclude CJD)