Measures of Variability
Measures if variability describe the average dispersion of data around a mean; most common = range, standard deviation and the standard error of the mean
Meta-analysis and Systematic Review
Meta-analysis is a tool for quantitative systematic review of observational studies and controlled trials that weights available evidence based on the numbers of patients included, the effect size, and often statistical tests of agreement with other trials
Phases of Clinical Research
Phases of clinical research are the steps taken to gather evidence to determine whether a novel intervention or treatment is safe and effective for clinical use
Propensity Score Analysis
Propensity analysis refers to statistical methods used to control for treatment selection bias in observational studies
Thoracic Trauma
Assessment of thoracic trauma requires the identification of immediately life-threatening injuries on primary survey, and delayed life threats on secondary survey.
Spinal Cord Anatomy and Syndromes
Spinal Cord Anatomy and Syndromes
Inhalation Injury
Inhalation Injury: 20% in burn patients; 60% in burns patients with central facial burns; causes a massive increase in mortality
Finger Thoracostomy
Finger Thoracostomy: Any pneumothorax in a patient undergoing positive pressure ventilation; Actual or near traumatic cardiac arrest; Shocked state with no apparent cause; Pleural drainage is not indicated in drowning or hangings unless pneumothorax is diagnosed. Remember pleural decompression will reduce the efficiency of the ACD and impedance valve
Extremity Injuries
The most important extremity injuries are those that are either life-threatening or limb-threatening in nature such as Pelvic disruption with massive hemorrhage; Severe arterial hemorrhage; and Crush syndrome
Electrical Injury
OVERVIEW Definitions Flow = change in P/resistance Change in P = flow x resistance V = IR Voltage = the tendency of electrons to move through a conductive system (volts)Resistance = tendency of a material to limit flow of electrons…
Compartment Syndrome CCC
Musculoskeletal compartment syndrome is a limb threatening condition resulting from increased pressure within a muscular compartment, which causes compression of the nerves, muscles and vessels within the compartment.
Digoxin
CLASS MECHANISM OF ACTION DIRECT:inhibition of Na/K ATPase on the cell surface-> increased intracellular Na+ and increased extracellular K+-> increased intracellular Ca2+ due to Na+/Ca2+ antiporter-> calcium-medated inotropy and increased automaticity, as well as negative dromotropy due to decreased intracellular K+ INDIRECT…