OVERVIEW organisms: Vibrio vulnificus and other species CLINICAL FEATURES tropical environments sea water borne cut to skin -> cellulitis -> necrotizing cellulitis profound multi-organ failure RISK FACTORS raw oyster consumption liver disease iron overload INVESTIGATIONS tissue culture blood cultures MANAGEMENT…
Léon Clément Le Fort (1829 – 1893) was a French surgeon. Eponym: Wagstaffe-Le Fort fracture (1886); Le Fort Operation for uterine prolapse; Le Fort amputation; Le Fort Male Catheter; and Le Fort sound. Godfather of FOAM 'Liberté de l'enseignement'
Waterborne Disease: major killer of the paediatric patient in the developed world
Stenotrophomonas maltophilia is an environmental global emerging Gram-negative MDRO that is most commonly associated with respiratory infections in humans
Spinal epidural abscess is considered a neurosurgical emergency; morbidity and mortality is worse with delayed diagnosis, and the worse the neurological deficit at the time of surgery the worse the outcome
Abdominal X-ray: AXR; Bowel obstruction; Sigmoid volvulus; Caecal volvulus; Bowel perforation
Arterial blood gas (ABG) is used to determine the adequacy of oxygenation and ventilation, assess respiratory function and determine the acid–base balance.
OVERVIEW classified according to serum-ascites albumin gradient (SAAG) CAUSES High SAAG (“transudate”) cirrhosis, hepatic failure, hepatic venous occlusion, constrictive pericarditis, kwashiorkor, cardiac failure, alcoholic hepatitis, liver metastasis Low SSAG (“exudate”) malignancy, infection (bacterial, fungal, Tb), pancreatitis, nephrotic syndrome, bowel obstruction…
numerous autoimmune markers will overlap between conditions and varying specificity and sensitivity
Peripheral blood film can provide useful information in diagnosing haematological conditions
Brain Natriuretic Peptide (BNP): released from ventricular myocytes in response to ventricular distension; role in regulation of salt and water excretion and BP management (ADH antagonist)
Co-trimoxazole: 2 antibiotics (sulfamethoxazole and trimethoprim) -> blocks two consecutive steps in the biosythesis of nucleic acids and proteins essential to bacteria.