CCC Critical Care compendium 340
Traumatic Brain Injury (TBI) Assessment

OVERVIEW TBI assessment involves: HISTORY General (AMPLE) Specifically: EXAMINATION Specifically in TBI assess: Evidence of base of skull fracture: Look for evidence of trans-tentorial herniation: Look for evidence of underlying causes and complications INVESTIGATIONS Bedside Laboratory Imaging References and Links

Robert Meyer (1864 - 1947) 340
Robert Meyer

Robert Meyer (1864 - 1947) was a gynaecologist and pathologist. Eponymously affiliated with the Weigert-Meyer rule he described in 1907. Meyer was recognised world wide as one of the founders of gynaecological pathology and for his contributions to embryology.

CCC Critical Care Compendium 680
Bronchiectasis DDx

Bronchiectasis is a suppurative lung disease characterised by the presence of permanently and abnormally widened (dilated) bronchial airways. Bronchiectasis may be the end result of a number of etiological processes.

CCC Critical Care compendium 340
Sepsis Biomarkers

Reviewed and revised 20 December 2015 OVERVIEW At least 178 different sepsis biomarkers have been described in the published medical literature, reflecting the complex pathophysiology of sepsis e.g. coagulation, complement, contact system activation, inflammation, and apoptosis also biomarkers of complications, e.g.…

CCC Critical Care compendium 340
Lithium Toxicity

Lithium: acute overdose is usually benign if adequate hydration is maintained and renal function is normal; chronic toxicity can be difficult to manage and result in devastating neurotoxicity

CCC Critical Care compendium 340
Methylene Blue

CLASS MECHANISM OF ACTION (1) low concentrations: methylene blue -> NADPH-dependent reduction to leucomethylene blue (due to action of methaemoglobin reductase) -> reduces methaemoglobin -> Hb(2) high concentrations: methylene blue -> converts ferrous iron of reduced Hb to ferric ion…