Description Paget’s disease of the nipple; disorder of the nipple-areola complex (NAC). Characterised chiefly by eczema like changes, it is a condition associated with underlying cancer of the breast. Clinical signs include: Hardening of the NAC Crusting A lumpy or…
Paget's disease of bone is a metabolic disorder of the bone, resulting in deformation and pain. It most commonly affects the axial skeleton; pelvis, lumbo-sacral spine, skull, femur and tibia. Diagnostic imaging is a key part of modern day diagnosis, and many cases are in fact incidental findings.
Description Köbner (Koebner) phenomenon – the appearance of isomorphic lesions following local trauma in skin areas that were not previously involved with the skin condition. That is, when patients with a cutaneous disease are stressed by exgternal cutaneous stimuli such…
Xeroderma pigmentosum (XP): rare autosomal recessive disorder of DNA repair characterised by photosensitivity, progressive pigmentary change, and an increased incidence of ultraviolet (UV)-induced skin and mucous membrane cancers.
Kaposi Sarcoma: An idiopathic pigmented sarcoma of the skin. Red nodules of varying size develop in the skin initially appearing on the sole of the foot then affecting the hands, progressing to affect the rest of the body.
Description History 1929 – First recorded 1963 – Reye, Morgan and Baral published in Lancet 1964 – George Johnson published after Influenza B outbreak 1979 – Starko et al statistically-significant link between aspirin use and Reye syndrome 1980 – CDC…
Description What is the actual eponymous medical sign/syndrome/repair/classification… History Associated Persons Philip Steven Wells Alternative names Name Name Controversies Did they first describe or popularise or plagiarise? References Wells PS, Anderson DR, Rodger M, Forgie M, Kearon C, Dreyer J, Kovacs…
Description What is the actual eponymous medical sign/syndrome/repair/classification… History Associated Persons Philip Steven Wells Alternative names Name Name Controversies Did they first describe or popularise or plagiarise? References Wells PS, Anderson DR, Rodger M, Stiell I, Dreyer JF, Barnes D, Forgie…
Mirizzi syndrome or extrinsic biliary compression syndrome, is a rare complication of cholelithiasis. Mirizzi syndrome is characterised by obstruction of the common bile duct (CBD), secondary to mechanical compression caused by the impaction of one or multiple gallstones in the neck of the gallbladder or cystic duct
Chilaiditi syndrome: symptomatic hepatodiaphragmatic interposition associated with abdominal pain, nocturnal vomiting, anorexia, and abdominal distension.
The Monro-Kellie doctrine or hypothesis states that the sum of volumes of brain, cerebrospinal fluid (CSF) and intracerebral blood is constant. An increase in one should cause a reciprocal decrease in either one or both of the remaining two.
Weigert (1877) and Meyer (1907): disposition of the ureter ectopic orifice lies caudal and medial to the orthoptic orifice was almost universal in cases of ureteral duplication. Weigert-Meyer Law.