Richard Clarke Cabot
Richard Clarke Cabot (1868-1939) American physician - clinical haematology; pioneering approach to social work; Cabot-Locke murmur (1903)
Gastroenterology
Ismar Isidor Boas
Ismar Isidor Boas (1858 - 1938) was a German gastroenterologist. Boas sign and Boas point (1894) Boas algesimeter (1891)
Hans Kehr
Biography Medical Eponyms Kehr sign Key Medical Contributions Courvoisier’s Law (1890) Courvoisier’s sign refers to the clinical observation that a painless, palpable, enlarged gallbladder in the presence of jaundice is more likely caused by malignant obstruction (e.g., carcinoma of the…
Einar Meulengracht
Jens Einar Meulengracht (1887 - 1976) was a Danish physician. Meulengracht ikterus index; Meulengracht diet; Gilbert syndrome
Portal vein thrombosis
Portal vein thrombosis: thrombus formation in the portal vein +/- tributaries (superior mesenteric vein, IMV and splenic vein)
Spontaneous Bacterial Peritonitis
Spontaneous Bacterial Peritonitis: often occurs in patients with severe hepatic dysfunction -> should lead to transplantation consideration if appropriate
Portal Hypertension
Portal Hypertension = increased resistance to flow through liver -> shunted around the other collateral vascular beds; the most common complication of cirrhotic liver disease
Hepatic veno-occlusive disease
Hepatic veno-occlusive disease aka sinusoidal obstruction syndrome (SOS) important complication of stem cell transplantation (SCT) mortality >30%
Acute Cholangitis
Acute or ascending cholangitis is a potentially life-threatening systemic infection resulting from inflammation and infection of the biliary tree due to bacterial growth in the bile, usually in the context of biliary obstruction
Gastrointestinal Literature Summaries
Gastrointestinal Literature Summaries
Coagulopathy in Liver Dysfunction
Coagulopathy in Liver Dysfunction; defined as INR >1.5 due to liver dysfunction; patients are not 'auto-anticoagulated' - they are often in a procoagulant state!
Clostridium difficile and PMC
Pseudomembranous colitis (PMC); acute inflammatory disease of colon commonly associated with antibiotic use; C. difficile implicated as a causative organism in 1970’s