Haemophagocytic lymphohistiocytosis
Haemophagocytic lymphohistiocytosis (HLH) may be inherited (AR; 5 subtypes, aka familial HLH) or acquired; may mimic severe sepsis, consider in apparent sepsis without source
Category Medical Specialty
Cryoprecipitate
Cryoprecipitate is prepared by thawing fresh frozen plasma (FFP) between 1°C and 6°C and recovering the precipitate
The cold-insoluble precipitate is refrozen.
Massive Transfusion Protocol
Reviewed and revised 10 March 2014 OVERVIEW Massive transfusion is defined as A Massive Transfusion Protocol should be used in critically bleeding patients anticipated to require massive transfusion GOALS IN MANAGEMENT OF MASSIVE TRANSFUSION THERAPY INDICATIONS IN MASSIVE TRANSFUSION MASSIVE TRANSFUSION…
Acute Cholangitis
Acute or ascending cholangitis is a potentially life-threatening systemic infection resulting from inflammation and infection of the biliary tree due to bacterial growth in the bile, usually in the context of biliary obstruction
Antibacterial Resistance
Antibacterial Resistance: Natural Resistance – they do not possess the molecular target of the drug or are impermeable to it; Acquired resistance – occurs through mutation or the acquisition of new genetic material carried by mobile elements
Antimicrobial Quick Reference
Antimicrobial Quick Reference
Antimicrobial Stewardship
Antimicrobial Stewardship is defined as ‘an ongoing effort by a health-care institution to optimise antimicrobial use among hospital patients in order to improve patient outcomes, ensure cost-effective therapy and reduce adverse sequelae of antimicrobial use (including antimicrobial resistance)’
Aspergillosis
Aspergillosis: fungal disease caused by the mold Aspergillus, ranging from hypersensitivity to invasive infection. Important species include Aspergillus fumigatus, niger, flavus, calavtus; transmission by inhalation; high mortality
Bacterial Meningitis
Bacterial meningitis = pyogenic infection of the cerebral ventricles and subarachnoid space -> CSF; usually confined to meninges (although in neonates and adults with Listeria monocytogenes -> cerebritis, encephalitis and abscesses can form)
Candidiasis
Diagnosis and treatment of candidiasis is a contentious issue; invasive candidiasis is difficult to diagnose; >150 species of Candida (a yeast), few are pathogens
Cholera
Cholera: Gastrointestinal infection caused by vibrio cholerae (Gram negative rod); transmission through consumption of contaminated drinking water or food
Cytomegalovirus in the Critically Ill
Cytomegalovirus (CMV) is a human herpesvirus (HHV) that rarely causes significant disease in immunocompetent people but is an important cause of illness in the immunocompromised