Renal Disease Biomarkers
Acute kidney injury (AKI) is a common problem in the critically ill associated with increased morbidity and mortality
Category Medical Specialty
Renal Transplant Patient
Renal Transplant; commonest transplant; anastamosed to common iliac artery and vein in the pelvis. the ureter is plumbed into the bladder; allows ease of access for palpation and biopsy
RIFLE Criteria and AKIN Classification
AKI can be defined as an abrupt (1 to 7 days) and sustained (more than 24 hours) decrease in kidney function. The ADQI formulated the RIFLE criteria in 2004 to allow for AKI to be objectively and uniformly defined.
Antimicrobial Dosing and Kill Characteristics
Dosing is different to non-critically ill patients
Different antimicrobials have different kill characteristics, which can be demonstrated on a concentration vs time graph for antibiotic activity
Paediatric Asthma
See RCH Melbourne Guidelines:
ILCOR Guideline Changes 2010
ILCOR = International Liaison committee on Resuscitation = conglomerate of resuscitation councils worldwide. Changes in 2010
Clenbuterol toxicity
Reviewed and revised 24 May 2014 OVERVIEW MECHANISM OF ACTION TOXICOKINETICS RISK ASSESSMENT CLINICAL FEATURES Effects include: Complications INVESTIGATIONS (Guided by clinical assessment) Laboratory tests MANAGEMENT Resuscitation Supportive care and monitoring Decontamination Disposition References and Links Journal articles
Renal replacement therapy: Fluid Management
Renal replacement therapy: Fluid Management
Ethanol Intoxication, Abuse and Dependence
Ethanol (ethyl alcohol) is an aliphatic alcohol, C2H5OH. The primary effect of ethanol is CNS depression, which is additive with other CNS depressants
High-dose Insulin Euglycaemic Therapy
High-dose Insulin Euglycaemic Therapy (HIET) is primarily used in the therapy of severe calcium channel blocker toxicity. HIET can also be used for severe beta blocker toxicity and potentially other toxicities/ presentations requiring inotropic support
Amphetamine Toxicity
Sympathomimetic syndrome with potential for life-threatening vascular complications (ischemia, dissection and haemorrhage). Note: ecstasy is also associated with hyponatraemia
End-Stage Renal Failure
End-stage renal failure has multiple implications for ICU management