Katz-Wachtel phenomenon

Katz-Wachtel phenomenon: Tall diphasic QRS complexes (>50 mm in height) in the mid-precordial leads (leads V2, V3 or V4) typically associated with Biventricular Hypertrophy (BVH).

This is the classic ECG pattern of BVH, most commonly seen in children with congenital heart disease e.g. ventricular septal defect (VSD).

Katz-Wachtel phenomenon Biventricular hypertrophy in a child with VSD
Katz-Wachtel phenomenon in child with isolated ventricular septal defect

The QRS amplitude is often confusingly large overlapping other precordial leads. Repeat the ECG at half standard calibration (5mm/mV instead of 10mm/mV) allows capture of the full QRS complex without overlapping with other leads.


History of Katz-Wachtel phenomenon

1937 – Katz and Wachtel suggested that large diphasic complexes in the standard limb leads were pathognomnic of congenital heart disease. They examined the ECGs of 43 children with congenital heart disease and proposed that the QRS contour may represent combined right and left ventricular ‘strain

A biphasic QRS (with the size of the two phases being of the order of less than 1 to 4) was a frequent finding in congenital heart disease. The presence of such a diphasic QRS is confirmatory of this diagnosis, and, when the two phases are large and of equal extent, the finding is pathognomonic of congenital heart disease.

Katz and Wachtel, 1937

1963 – Elliott reviewed electrographic and vectorcardiographic criteris for biventricular hypertrophy. They found…

The vectorcardiograms and electrocardiograms in 10 infants with congenital malformations of the heart have been described. Each malformation demonstrated combined ventricular hypertrophy…One common denominator in each of the 10 patients was large large diphasic complexes over 50 mm in either leads V2, V3, V4 were observed in the electrocardiogram of each case of biventricular hypertrophy studied.

These tall mid-precordial QRS complexes have been called the Katz-Wachtel phenomenon and presumably reflect combined ventricular hypertrophy.

Elliott 1963
Elliott Combined Ventricular Hypertrophy in Infancy 9163

FIG. 4. Case 7. Biventricular hypertrophy in a 17 month old boy with severe anaemia and congenital deformity of the mitral valve. ECG shows biventricular hypertrophy: tall R wave in lead V1 and V2; tall RS complexes in lead Vs over 70 mm; deep S wave in lead V1; and relatively tall R waves in leads V5, and V6 preceded by a deep Q wave. Elliott 1963

Associated Persons

Alternative names
  • Katz-Wachtel sign

References

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LITFL Further Reading

Cite this article as: Mike Cadogan and Robert Buttner, "Katz-Wachtel phenomenon," In: LITFL - Life in the FastLane, Accessed on August 11, 2022, https://litfl.com/katz-wachtel-phenomenon/.

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Associate Professor Curtin Medical School, Curtin University. Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM Sir Charles Gairdner Hospital.  Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

MBBS (UWA) CCPU (RCE, Biliary, DVT, E-FAST, AAA) Adult/Paediatric Emergency Medicine Advanced Trainee in Melbourne, Australia. Special interests in diagnostic and procedural ultrasound, medical education, and ECG interpretation. Editor-in-chief of the LITFL ECG Library. Twitter: @rob_buttner

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