Toxicology-Library-Toxicant-Drug-340-256
Benztropine toxicity

Normally used to ameliorate dyskinesia from antipsychotics but has been used for recreational purposes. Benztropine is a potent anticholingeric in overdose. You may also use it yourself as an antidote for an acute dystonic reaction.

Toxicology-Library-Toxicant-Drug-340-256
Clozapine toxicity

Clozapine is an atypical antipsychotic, due to its restricted use an acute overdose is a rare event but clinicians should be aware that coma can occur and management is with supportive care. In chronic toxicity agranulocytosis and myocarditis can occur, these are not features of an acute poisoning but monitored in patients with long term therapeutic use.

Toxicology-Library-Toxicant-Drug-340-256
Lithium toxicity

Lithium is commonly used to treat bipolar, for your toxicology encounter it will come in two varieties, either an acute overdose or chronic toxicity and it is important to distinguish the two (examiners love this question).

Toxicology-Library-Toxicant-Drug-340-256
Olanzapine toxicity

Olanzapine is a second generation atypical antipsychotic. Widely used in Australasia and therefore a fairly common presentation to the emergency department. Olanzapine like queitiapine has a predictable dose-dependent CNS depression.

Toxicology-Library-Toxicant-Drug-340-256
Phenothiazines and butyrophenones

Phenothiazines and butyrophenones are the antipsychotic (neuroleptic) agents. Commonly used agents are chlorpromazine, prochlorperazine, droperidol and haloperidol. Other unfamiliar agents include fluphenazine, Pericyazine, Pipothiazine and Trifluoperazine

Toxicology-Library-Toxicant-Drug-340-256
Quetiapine toxicity

Quetiapine is a second generation atypical antipsychotic. Widely used in Australasia and therefore a fairly common presentation to the emergency department. Quetiapine is associated with a predictable dose-dependent CNS depression.

Tropical Medicine Library 340
Tetanus Vaccine

Indications and Role:The tetanus immunization is not a live virus vaccine. A toxoid is created from the virus to form an immune reaction against the toxin produced by the bacteria. Tetanus vaccines are only given as part of combined products…