Effects of Anaesthetic Agents on the Developing Brain
There is concern that sedatives and anaesthetic agents may have harmful effects on the developing brain
Selective Lung Ventilation
Selective Lung Ventilation involves the isolation of one lung from the other allowing independent ventilation. Usually performed with a double lumen tube (DLT); alternatives are the use of a univent tube or an endobronchial blocker
Cleaning Bronchoscope
Cleaning Bronchoscope. The technique described uses the Matrix biofilm remover as a detergent.
Reye syndrome
Description History 1929 – First recorded 1963 – Reye, Morgan and Baral published in Lancet 1964 – George Johnson published after Influenza B outbreak 1979 – Starko et al statistically-significant link between aspirin use and Reye syndrome 1980 – CDC…
Antibiotic Guidelines in ICU
Antibiotic guidelines vary between ICUs. This variation is based on local causes of infections, resistance patterns, availability and patient factors. However, the principles of appropriate use of antibiotics are universal... as are the common errors!
Pulseless Electrical Activity
Pulseless electrical activity (PEA) occurs when organised or semi-organised electrical activity of the heart persists but the product of systemic vascular resistance and the increase in systemic arterial flow generated by the ejection of the left ventricular stroke volume is not sufficient to produce a clinically detectable pulse
Resuscitation Literature Summaries
Resuscitation Literature Summaries
Selective Aortic Arch Perfusion
Selective Aortic Arch Perfusion: Lecture by Jim Manning on Selective Aortic Arch Perfusion given to GSA HEMS
Leg ulcers DDx
Leg ulcers may result from venous stasis, ischemia, malignancy, infection, neuropathy, trauma or underlying systemic disease.
Data Distributions
Data can be described by different distributions, which has implications for how the data is analysed using statistical methods
Fisher’s Exact Test
Fisher's Exact Test is to compare categorical data; more complicated to perform than the Chi square test; only generally applicable in 2 x 2 contingency table
Hazard Ratio, Median Ratio and Kaplan-Meier Curves
Time-to-event curves analyzed by Cox proportional hazards regression are useful for analysing events occurring over time; uses all available information, including patients who fail to follow up or reach the endpoint (censored data)