Medical milestones, landmark publications, and notable births and deaths associated with November 4.

Events

1821 – George Kellie (1770-1829) performed post-mortem examinations on two people who died in a storm in Leith, near Edinburgh on the morning of the November 4, 1821. His findings underpinned the Monro–Kellie doctrine. Monro had described the fixed-volume cranial concept earlier; Kellie’s contribution was correlating it with pathological observations from these post-mortems

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Births

1851 – Hans Chiari (1851-1916), Austrian pathologist; described Budd–Chiari syndrome (1899), Arnold–Chiari malformation (1896)

1888 – Wilhelm Lutz (1888-1958), Swiss dermatologist; described Lewandowsky-Lutz dysplasia (1922), Lutz-Miescher syndrome (elastosis perforans serpiginosa) (1953), Lutz sign (Asboe-Hansen sign)(1957)

1896 – William Thomas Lemmon (1896-1974), American surgeon; developed and performed continuous spinal anaesthesia (1939) and the Lemmon mattress

1909 – David Abramson Rytand (1909-1991), American physician and cardiologist; described Rytand murmur (1946), and Rytand’s Law (1951)

1917 – Alan Lyell (1917-2007), Scottish Dermatologist; described Lyell Syndrome (1956) aka Toxic epidermal necrolysis

1929 – Charles Rufus Baxter (1929-2005), American physician; introduced the Parkland Formula for Burns (1968)

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Deaths

1837 – Baron Jean-Louis-Marc Alibert (1768-1837), French dermatologist; described Alibert-Bazin syndrome (1825), Alibert disease (1816), and Alibert mentagra (1825)

1914 – Moritz Roth (1839-1914), Swiss pathologist; described Roth spots (1872)

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Further reading

• Kellie G. On Death from Cold and on Congestions of the Brain. An account of the appearances observed in the dissection of two of three individuals presumed to have perished in the storm of the 3rd, and whose bodies were discovered in the vicinity of Leith on the morning of the 4th, November 1821: with some reflections on the pathology of the brain. Transactions of the Medico-Chirurgical Society of Edinburgh 1824;1:84-169