CCC Critical Care compendium 340
Polyuria Hot Case

GENERAL APPROACH Causes Alcohol induced diuresis Osmotic diuresis (mannitol therapy) Cerebral salt wasting Diabetes insipidus Hypertonic saline administration Hypertensive diuresis Appropriate response to fluid therapy Hyperglycaemia Volume statusComplicationsTreatment INTRODUCTION CUBICLE INFUSIONS inotropes/vasopressors to maintain CPP IVF boluses hypertonic saline osmotherapies…

CCC Critical Care compendium 340
Jaundice Hot Case

GENERAL APPROACH Acute, Chronic or Acute on Chronic Liver Disease Pre Intra Post INTRODUCTION CUBICLE dialysis machine – evidence of multi-organ failure Level 1 infuser – significant bleeding malena INFUSIONS blood products octreotide 10% dextrose terlipressin VENTILATOR strategy (protective lung…

CCC Critical Care compendium 340
TRALI

Transfusion related acute lung injury (TRALI) is defined as hypoxia and bilateral pulmonary edema occurring during or within 6 h of a transfusion in the absence of other causes such as cardiac failure or intravascular volume overload

CCC Critical Care compendium 340
Blood Products

This page is due for revision. OVERVIEW IMPORTANT INDICATIONS Packed red blood cells (PRBCs) Platelets FFP Cryoprecipitate Prothrombin complex concentrate (PCC) Granulocyte concentrate IV immunoglobulin Factor 7 DOSES IN PAEDIATRICS BLOOD PRODUCT COMPATIBILITIES References and Links

CCC Critical Care compendium 340
Storage Lesions

Storage lesions are the adverse effects associated with the storage of blood; begins after about 2 weeks of storage and progresses with duration of storage ('RBC age')

CCC Critical Care compendium 340
Hepatopulmonary Syndrome

Hepatopulmonary Syndrome = hepatic dysfunction + intrapulmonary vasodilation -> gas exchange abnormalities; imbalance between intrapulmonary vasoconstriction and vasodilation at the pre- and post-capillary level