Renal and Urological Toxicity of Chemotherapy
Renal and Urological Toxicity of Chemotherapy: chronic renal failure; acute renal failure; renal tubular dysfunction; haemorrhagic cystitis; dysuria
Peripartum Cardiomyopathy
Peripartum Cardiomyopathy = dilated cardiomyopathy of unknown cause that occurs in the peripartum period; rare (1 in 15,000 deliveries); fatal in up to 50% of patients
Physiology of Pregnancy
Physiology of Pregnancy
Pneumonia in Pregnancy
Pneumonia in Pregnancy: 2 patients; treatment dependent on stage of pregnancy (first trimester: avoidance of teratogenicity, third trimester: prevention of pre-term labour)
signs of severe sepsis may be masked by normal pregnancy changes
Pre-eclampsia and Eclampsia
Pre-eclampsia and Eclampsia: multisystem disorder of pregnancy characterised by hypertension and organ system derangement; defective trophoblast invasion of the spiral arteries and abnormal trophoblast differentiation.
Pregnancy and Intensive Care
Pregnancy and Intensive Care: Common reasons for admission include hypertensive disorders; haemorrhage; respiratory failure; sepsis; trauma
Status Asthmaticus and Pregnancy
Status Asthmaticus and Pregnancy: dangerous situation; 2 patients; complex; need to call for help early; pregnancy related issues are dependent on stage of pregnancy
Trauma and Pregnancy
Trauma and Pregnancy: leading cause of non-obstetric maternal mortality -> also has a high chance of fetal loss; ATLS approach (primary and secondary survey) including safe transport to trauma centre with obstetric care.
VTE and Pregnancy
Venous thromboembolism in pregnancy: 25% of maternal mortality; x 5 increase in risk (venous stasis, hypercoaguable, vascular injury from delivery)
Cardiac Toxicity of Chemotherapy
Cardiac Toxicity of Chemotherapy
Haematological Toxicity of Chemotherapy
Haematological Toxicity of Chemotherapy: Anaemia; Thrombocytopaenia; Marrow hypoplasia; Thrombotic Microangiopathy; Haemostasis Disorders; Induced Leukaemia; Impaired Cell-mediated Immunity
Adverse Drug Reactions
Adverse Drug Reactions