CCC Critical Care compendium 340
Oxygen-Haemoglobin Dissociation Curve

sigmoid shape of the oxy-Hb dissociation curve results from the allosteric interactions of the globin monomers that make up the haemoglobin tetramer as each one binds O2. Multiple factors can affect the affinity of Hb for oxygen, thus causing the curve to shift to the left (increased oxygen affinity) or to the right (decreased O2 affinity)

CCC Critical Care compendium 340
Hyperkalaemia CCC

Clinical Cases Hyperkalaemia DDx Hyperkalaemia management Hyperkalemia Case Study Causes of HYPERkalaemia Serum potassium levels above the normal range (3.5-5.0 mmol/L) 1) Increased potassium intake (rare) Oral (potassium supplements) IV (transfusion of stored blood, supplement infusions) 2) Increased production Tissue…

CCC Critical Care Compendium 680
Parkinsonism

Parkinsonism is a combination of resting tremor, rigidity, bradykinesia, and loss of postural reflexes. Parkinson disease (PD) is the most common form, but must be distinguished from its imitators.

CCC Critical Care compendium 340
Fluid balance

Daily fluid balance is the daily sum of all intakes and outputs, and the cumulative fluid balance is the sum total of fluid accumulation over a set period of time. The harmful effects of positive fluid balance and the importance of deresuscitation