Category Eponymictionary
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Löffler syndrome

Löffler (Loeffler) syndrome is a transient, self-limiting, and benign pulmonary eosinophilia, characterised by pulmonary opacities on X-ray, elevated blood eosinophils and an acute onset of potential symptoms of mainly cough and dyspnoea.

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Sutton’s Law

Sutton's law: When making a diagnosis one should first consider the obvious, and conduct tests which could confirm/ rule out the most likely diagnosis.

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Osler node

Osler node: Painful, red, raised lesions usually found on the palms and soles. Caused by immune complex deposition and the resulting inflammatory response.

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Kerley lines

Peter James Kerley first described horizontal lines that he postulated to be peri-vascular lymphatics in patients with mitral stenosis and left ventricular failure

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Rigler sign

Radiographic sign of pneumoperitoneum. Air in the peritoneum and air within the intraluminal spaces outline the luminal and serosal surfaces of the bowel wall.

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Willis-Ekbom disease

Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is characterized by an urge to move the legs, usually associated with limb discomfort. The symptoms occur at rest, are relieved by movement, and are worst in the evening and at night.

Koplik Spots

Description What is the actual eponymous medical sign/syndrome/repair/classification… History 1778 – John Quier 1785 – JA Murray 1854 – Reubold 1871 – Carl Jakob Adolf Christian Gerhardt (1833-1902) 1877 – Bohn 1880 – Nikolaj Flindt (1843-1913) 1897 – Nicolai Feodorowitsch…

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Paget’s disease of the nipple

Description Paget’s disease of the nipple; disorder of the nipple-areola complex (NAC). Characterised chiefly by eczema like changes, it is a condition associated with underlying cancer of the breast. Clinical signs include: Hardening of the NAC Crusting A lumpy or…

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Paget’s disease of bone

Paget's disease of bone is a metabolic disorder of the bone, resulting in deformation and pain. It most commonly affects the axial skeleton; pelvis, lumbo-sacral spine, skull, femur and tibia. Diagnostic imaging is a key part of modern day diagnosis, and many cases are in fact incidental findings.

Köbner (Koebner) phenomenon

Description Köbner (Koebner) phenomenon – the appearance of isomorphic lesions following local trauma in skin areas that were not previously involved with the skin condition. That is, when patients with a cutaneous disease are stressed by exgternal cutaneous stimuli such…

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Xeroderma pigmentosum

Xeroderma pigmentosum (XP): rare autosomal recessive disorder of DNA repair characterised by photosensitivity, progressive pigmentary change, and an increased incidence of ultraviolet (UV)-induced skin and mucous membrane cancers.