One of the first signs of vertebral metastases is disappearance of the pedicle on the AP X-ray. This is known as the 'absent pedicle' or 'winking owl sign'.
Frederic Jay Cotton (1869–1939) was an American Orthopedic Surgeon. Eponymously affiliated with the Cotton fracture (trimalleolar fracture) and Cotton-Loader position (hyper-flexed wrist with ulna deviation in closed reduction of distal radius fractures)
Cotton fracture (trimalleolar fracture) described in 1915 by Frederic Jay Cotton (1869-1939); fracture of the ankle that involving the lateral malleolus, medial malleolus and distal posterior aspect of the tibia (posterior malleolus).
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