Baclofen in overdose produces a rapid onset of delirium, respiratory depression, coma and seizures. In large overdose the patient can appear brain dead and it has resulted in the pursuit of organ donation only for the patient to wake on the operating table. The mainstay of treatment is good supportive care.
A 57 year old man presents to the ED with 18 hours of severe upper abdominal pain, fever, nausea and vomiting. He looks jaundiced, his HR is 120bpm, BP 110/60, RR 22 and his temperature is 37.8oC. He is tender and guarded in his right upper quadrant on abdominal palpation.
List the complications and their likely underlying mechanisms specifically related to cardiopulmonary bypass that may be seen in the Intensive Care Unit following cardiac surgery.
A 76-year-old female is admitted to the ICU following elective aortic and mitral valve replacement. Transoesophageal echo assessment at the end of surgery showed an ejection fraction of 20%. Her preoperative creatinine was 340 micromol/L. Total bypass time was 240 minutes.
With regards to the determination of brain death; list the preconditions that must be met prior to the determination of brain death by clinical criteria
Funtabulously Frivolous Friday Five 189 - Just when you thought your brain could unwind on a Friday, some medical trivia FFFF.
A 70 year old man was admitted to hospital with a "viral illness". A peripheral IV cannula was inserted into his right cubital fossa
This week’s guest, Australian intensivist Dr Ed Litton, truly amazes and inspires me. Despite having a full-time clinical and research career, and a young family, Ed pursues his passion for adventure mostly through ultra-endurance exercise.
A 55 year old man presents with a good chest pain story that makes you nervous. A review of ST elevation in aVR and LMCA Stenosis
Sir David Drummond (1852–1932) was an English physician. Drummond sign of tracheal whiff with thoracic aortic aneurysm 1908
Redback spider bite is the most common envenoming in Australia with 5000–10,000 human bites occurring annually.
The art of observation is central to the art of medicine, and William Osler was its greatest teacher. Here are some more lessons from the master.