Pancytopaenia
Pancytopaenia
Oozing from a Venepuncture Site
An approach to the patient with persistent bleeding from a venepuncture site
Lupus Anticoagulants
OVERVIEW Lupus Anticoagulants -> result in acquired hypercoagulability due to poorly understood actions ? alteration of the regulation of haemostasis and endothelial cell injury ASSOCIATIONS MANAGEMENT (1) APTT (2) dilute Russell viper venom time (3) silica clotting time(4) kaolin clotting…
Isolated Elevated APTT
Isolated Elevated APTT
Thyroid Storm
Thyroid Storm: life threatening exacerbation of hyperthyroid state with 1 or more organ dysfunction
Pheochromocytoma
Pheochromocytoma: paraganglioma -> catecholamine producing tumours; associated with: MEN, von Hippel-Lindau syndrome, neurofibromatosis and familial paragangliomas
Myxoedema Coma
Myxoedema Coma: extreme form of hypothyroidism; high mortality
Haemolytic Uraemic Syndrome
Haemolytic uraemic syndrome (HUS) is a clinically similar condition to TTP; in HUS (unlike TTP): renal failure > neurological symptoms
Haemolytic anaemia
Reviewed and revised 27 October 2016 OVERVIEW Definition Shortened lifespan can be due to RBC destruction from: The approach to haemolytic anaemia involves: In the critically ill, always consider: PATHOGENESIS Haemolysis can occur intravascularly or extravascularly, or both Immune-mediated Non-immune…
Haematology Literature Summaries
Haematology Literature Summaries
Haematological Emergencies
almost all haematological malignancies are curable with modern treatments such as chemotherapy, radiotherapy, immunotherapy and bone marrow transplantation
Disseminated intravascular coagulation
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by the intravascular activation of coagulation with loss of localization arising from different causes