Reviewed and revised 26 August 2015 OVERVIEW Clinical trials are planned to stop when one of the following is reached sample size event count length of follow up goal scheduled date of closure Unplanned early stopping of trials may occur…
Receiver Operating Characteristic (ROC) curves plot sensitivity versus false positive rate for several values of a diagnostic test
Risk is a nebulous term in evidence-based medicine, as it may refer to either relative or absolute risks. Overall, absolute risks are more meaningful and can be converted in 'numbers need to treat' (NNT), which are useful in the clinical setting
Case-Control Studies: a type of retrospective observational study; control patients are ‘matched’ using some criteria (age, gender), typically should have no history of the disease of interest and should be representative of the general population
Causes of HYPOcalcaemia: Commonest causes: HYPOalbuminaemia and HYPERventilation
IDEAL BODY WEIGHT DOSING BODY WEIGHT LEAN BODY WEIGHT
Uric acid is the major end metabolite of purine. Purine found in nucleic acid and exogenous sources; Commonly used as marker for gout and pre-eclampsia; Levels do not usually indicate severity of disease
It's Friday. Boggle your brain with FFFF challenge and some old fashioned trivia. Funtabulously Frivolous Friday Five 266
Echocardiography in acute myocardial infarction is useful for identification of regional wall motion abnormalities and complications
Hyperbaric Oxygen Therapy. Carried out in a pressurised chamber (single or multiple patients). Treatments typically between 2 and 3 ATA
Cryptogenic Organising Pneumonia (COP) is also known as bronchiolitis obliterans organising pneumonia (BOOP); not the same as bronchiolitis obliterans; the rapidly progressive form has a very poor prognosis
The LITFL Critical Care Compendium (CCC) has numerous entries on sepsis, this page collates them