Glucagon Therapy
Agonist at glucagon-specific Gs-protein coupled receptor, activates adenylyl cyclase resulting in increased [cAMP]i
Calcium Channel Blocker Toxicity
Severe calcium channel blocker toxicity is highly lethal, as a result of cardiovascular collapse. Good outcomes can be achieved through aggressive treatment and provision of circulatory support
William Heberden the Elder
William Heberden the Elder (1710 - 1801) was an English physician
Floppy infant DDx
Floppy infants have globally decreased muscle tone, but can be either 'weak' or 'strong' corresponding to lower or upper motor neuron lesions respectively.
Intracranial Structures and Contrast
Intracranial Structures That Exhibit Contrast Enhancement. CT Head with contrast is usually performed to identify mass lesions or vascular abnormalities.
Exophthalmos DDx
Exophthalmos is abnormal protrusion of the eyeball or eyeballs. Differential diagnosis
Eye Trauma DDx
Differential diagnosis of eye trauma. Trauma can result in a range of injuries, both blunt and penetrating.
Shigeo Satomura
Shigeo Satomura (1919 - 1960) was a Japanese scientist. Designed and developed the Doppler Cardiograph, blood-rheograph and trasncutaneous flowmeter
Transpulmonary pressure (TPP)
Transpulmonary pressure (TPP) is the net distending pressure applied to the lung by contraction of the inspiratory muscles or by positive-pressure ventilation
Patient-Ventilator Dyssynchrony
OVERVIEWPatient-Ventilator Dyssynchrony occurs when the patient’s demands are not met by the ventilator, resulting from problems with: VENTILATION STRATEGIES Total Ventilator-controlled Mechanical Support: Partial Patient-Controlled Mechanical Support: CAUSES Patient factors Ventilator factors TYPES OF VENTILATOR DYSSYNCHRONY Ineffective triggering Inappropriate triggering…
De-escalation
De-escalation: Determine if safe for medical intervention. Determine cause - usually delirium with an underlying medical cause, substance abuse or withdrawal or psychiatric disorders
Physical Restraint
Reviewed and revised 30 July 2014 OVERVIEW INDICATIONS CONTRA-INDICATIONS ASSESSMENT APPROACH TO PHYSICAL RESTRAINT Exclude other therapeutic options first Ensure safety at all times Prepare physical restraint team Initiate manual restraint During manual restraint Monitoring (according to depth of sedation) may…