CCC Critical Care compendium 340
Hypoxaemia in Toxicology

AGENTS CLINICAL FEATURES INVESTIGATIONS SPECIFIC MANAGEMENT AND TRIGGERS FOR INTERVENTION Cyanide Carbon monoxide Methaemoglobinaemia References and Links

CCC Critical Care compendium 340
Liver Transplantation for Paracetamol Toxicity

Paracetamol overdose is the most common cause of fulminant hepatic failure in the USA (39% of cases). Paracetamol-induced hepatotoxicity is defined as a peak elevation in hepatic transaminases (ALT or AST) > 1000 IU/L in the context of paracetamol overdose

CCC Critical Care compendium 340
Methaemoglobinaemia

Reviewed and revised 14 September 2014 OVERVIEW Methaemoglobinaemia is the state of excessive methaemoglobin in the blood CAUSES Congenital Acquired (toxin/drugs) CLINICAL FEATURES INVESTIGATIONS MANAGEMENT Resuscitation Specific therapy Supportive care and monitoring REASONS FOR FAILURE OF METHYLENE BLUE Consider the…

CCC Critical Care compendium 340
Sympatholytic toxidrome

True sympatholytic agents (e.g. alpha-blockers like phentolamine, and vasodilatory agents such as GTN, SNP, etc)≥ Also beta-blocker; ca2+ blocker;
clonidine; digoxin

CCC Critical Care Compendium 680
High airway pressure DDx

High airway pressures in the intubated patient can signify the presence of a life-threatening emergency. The underlying cause is either with the 'man or the machine' (patient versus equipment). A structured approach to this problem is essential.

CCC Critical Care Compendium 680
Massive haemoptysis DDx

Haemoptysis is the symptom of coughing up blood. Massive haemoptysis has no generally accepted definition. Suggested volumes range from 100 mL to more than 1000 mL. A more relevant definition of massive haemoptysis is the volume that is life threatening by virtue of airway obstruction or blood loss (anatomical dead space is only 100-200 mL)