Wolff-Parkinson-White (WPW) Syndrome is a combination of the presence of a congenital accessory pathway and episodes of tachyarrhythmia.
WPW syndrome is characterized by a double stimulation of the ventricles. A premature conduction wave via accessory pathways (preexcitation) stimulates the portions of the ventricles nearest the atrium; then the ventricles depolarize as a result of the conduction wave which proceeds normally through the atrioventricular (AV) node.
The clinical significance of this syndrome depends on the appearance of (supraventricular) reentry tachycardias.
1915 – Frank Norman Wilson (1890–1952) first to describe the condition [Wilson FN, 1915]
1921 – Alfred M. Wedd (1887–1967) next to describe the syndrome [Wedd AM, 1921]
1928 – On April 2 a young man was referred to Paul Dudley White because his physician was perplexed by the occurrence of paroxysmal atrial fibrillation in a healthy individual. White was preparing for visits to overseas medical centers and took the ECG’s with him.
- Vienna: the tracing was deemed to represent nothing more unusual than bundle-branch block and atrioventricular (AV) nodal rhythm
- London: Parkinson was interested and found a further seven cases to add to the four from Boston.
1930 – Wolff L, Parkinson J, and White PD publish the eleven cases as definitive description of the syndrome – ‘Bundle Branch Block with Short P-R Interval in Healthy Young People Prone to Paroxysmal Tachycardia.’
Wolff first met Parkinson many years later at the Second World Congress of Cardiology in 1954
- Pre-excitation Syndromes – LITFL ECG Library
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