Noonan’s syndrome is an autosomal dominant genetic condition with mutations affecting the RAS signaling pathway. Jacqueline Anne Noonan (1921 – )
Palla sign (1983) right descending pulmonary artery enlargement and ‘sausage-shaped’ appearance as a potential sign of pulmonary embolism on chest XR
The Hampton hump is a well-defined pulmonary pleural based opacity representing hemorrhage and necrotic lung tissue in a region of pulmonary infarction caused by acute pulmonary embolism.
Description What is the actual eponymous medical sign/syndrome/repair/classification… History 1952 – Margaret Dix and Charles Hallpike published a landmark paper in neuro-otology, looking at the three most common peripheral vertigo diseases: Meniere’s disease, vestibular neuritis and benign paroxysmal positional nystagmus. They described a clinical bedside manoeuvre in detail, “Lagerungs Manoeuvre”, known now as the Dix-Hallpike […]
Chang sign (1965) Dilated descending pulmonary artery associated with pulmonary infarction and pulmonary hypertension following pulmonary embolism
Description What is the actual eponymous medical sign/syndrome/repair/classification… History Associated Persons Henry Meige (1866 – 1940) Alternative names Brueghel’s syndrome Blepharospasm-oromandibular dystonia syndrome Controversies Did they first describe or popularise or plagiarise? References Altrocci PH. Spontaneous oral-facial dyskinesia. Archives of Neurology 1972; 26 :506-512 Tolosa ES, Klawans HL. Meige’s disease: A clinical form of facial […]
Tolosa-Hunt syndrome is a severe unilateral periorbital headache and ophthalmoplegia resulting from a non-caseating granulomatous inflammation of the cavernous sinus and/or superior orbital fissure.
Vitreous, retrohyaloid, retinal, or subretinal haemorrhage occurring consequent to an acute intracranial haemorrhage or elevated intracranial pressure.
Description What is the actual eponymous medical sign/syndrome/repair/classification… History 1838 – Jean Etienne Dominique Esquirol (1772-1840), a founder of modern alienism (psychiatry). 1846 – Edouard Onesimus Séguin (1812–1880) was one of the first to outline a complete plan for the training of mental defectives. In his classic 1846 textbook, Séguin discusses the Alpine and lowland […]
Mees lines: white bands traversing the full width of the nail, running parallel to the lunula, with no palpable ridges. As the nail grows they bands move distally and finally disappear when trimmed. The finding was initially related to acute arsenic poisoning.