Serious Generalised Skin Disorders: Mnemonic: PTSD-D
= immune complex mediated hypersensitivity -> severe erythema multiforme. Separation of the epidermis from the dermis; most authors believe toxic epidermal necrolysis (TEN) and SJS are different ends of the same spectrum of disease
CAUSES Meningococcal disease Post-splenectomy pneumococcaemia DIC Rickettsial infections High dose inotropes Endocarditis Venom-induced consumptive coagulopathy (VICC) due to snakebite
Heinrich Köbner (1838 – 1904) was a German dermatologist. Eponym: Koebner phenomenon; Köbner syndrome (Epidermolysis bullosa simplex)
Moriz 'Kohn' Kaposi (1837 – 1902) was a Hungarian physician and dermatologist. Provided first, descriptions of systemic lupus erythematosus (1869/1872); Kaposi Sarcoma (1872); xeroderma pigmentosum (1882); lichen ruber moniliformis (1886); and varicelliform eruption (1887)
Kaposi Sarcoma: An idiopathic pigmented sarcoma of the skin. Red nodules of varying size develop in the skin initially appearing on the sole of the foot then affecting the hands, progressing to affect the rest of the body.
Biography Born 12 April 1887, Luzern 1909-1912 Studied medicine in Zürich, Berlin, and Berne 1914 – MD, Berne 1915 – Postgraduate studies at the paediatric clinic in the Charité, Berlin 1929 – Privatdozent in paediatrics, Berne 1932 – Professor and Director…
Alan Lyell (1917-2007) was a Scottish Dermatologist. Lyell Syndrome (1956) AKA toxic epidermal necrolysis.
Ferdinand Karl Franz Schwarzmann, Ritter von Hebra (1816-1880) was an Austrian physician and dermatologist. Founder New Vienna School of Dermatology
Eduard Heinrich Henoch (1820 – 1910) was a German Paediatrician. Student of Johann Lukas Schönlein, he extended the clinical features of childhood purpura and is eponymously affiliated with Henoch-Schönlein Purpura
John Addison Fordyce (1858 –1925) was an American dermatologist. Eponymously affiliated with Fox–Fordyce disease
Fox–Fordyce disease: A chronic itchy papular condition occurring in areas of the skin with apocrine glands especially the axilla of young women.