Pharmacokinetics and ECMO
ECMO support has potential implications for pharmacotherapy in the critically ill, the significance of which are poorly defined; Pharmacokinetic effects of ECMO vary with different drugs and drug characteristics
Acalculous cholecystitis
Acalculous cholecystitis: pathophysiology: bile stasis + increased viscosity c/o fever, dehydration, no enteral feeding -> CCK induced gall bladder contraction with wall ischaemia
Post hemihepatectomy care
Hemihepatectomy: major surgery; perioperative mortality = 3%; usual indication = metastatic colorectal adenocarcinoma or cholangiocarcinoma
Trauma Scoring Systems
There are various systems available for scoring trauma severity. Some are based on anatomical descriptions of injuries, some on physiological parameters and others use combined data. No ideal trauma scoring system is currently available
Trauma Literature Summaries
Trauma Literature Summaries: Tranexamic acid (TXA) for traumatic haemorrhage; Steroids for acute spinal injury
Dipstick urinalysis
Urinalysis (UA) is used as a screening and/or diagnostic tool to detect substances or cellular material in the urine associated with metabolic disorders, renal dysfunction or urinary tract infections (UTI)
Pyloric Stenosis
Pyloric Stenosis is a medial emergency that requires urgent fluid resuscitation and resolution of biochemical abnormalities. Definitive surgical treatment can then be undertaken to restore enteral nutrition.
The Septic Child
The Septic Child
Effects of Anaesthetic Agents on the Developing Brain
There is concern that sedatives and anaesthetic agents may have harmful effects on the developing brain
Selective Lung Ventilation
Selective Lung Ventilation involves the isolation of one lung from the other allowing independent ventilation. Usually performed with a double lumen tube (DLT); alternatives are the use of a univent tube or an endobronchial blocker
Cleaning Bronchoscope
Cleaning Bronchoscope. The technique described uses the Matrix biofilm remover as a detergent.
Reye syndrome
Description History 1929 – First recorded 1963 – Reye, Morgan and Baral published in Lancet 1964 – George Johnson published after Influenza B outbreak 1979 – Starko et al statistically-significant link between aspirin use and Reye syndrome 1980 – CDC…