Löffler (Loeffler) syndrome is a transient, self-limiting, and benign pulmonary eosinophilia, characterised by pulmonary opacities on X-ray, elevated blood eosinophils and an acute onset of potential symptoms of mainly cough and dyspnoea.
Wilhelm Löffler (1887 – 1972) was a Swiss physician. Löffler is eponymously associated with two clinical manifestations of eosinophilia which he described: transient pulmonary infiltrates with eosinophilia (Löffler syndrome, 1932) and endocarditis parietalis fibroplastica (Löffler endocarditis, 1936).
Description Osler node: Painful, red, raised lesions usually found on the palms and soles. Caused by immune complex deposition and the resulting inflammatory response. Associated with a number of conditions, including infective endocarditis, SLE, and disseminated gonococcal infection. To be differentiated from painless Janeway lesions History 1885 – Osler, in a series of three Gulstonian […]
Benjamin Sacks (1896 – 1971) was an American physician. 1924 – Along with Emanuel Libman defined atypical verrucous valvular lesions in patients with SLE (Libman–Sacks endocarditis)
C. H. Joseph Chang (1929 – 2017) was an American radiologist. Chang sign (CXR finding in pulmonary embolus) decribed in 1965
Aubrey Otis Hampton (1900 – 1955) was an American Radiologist. Eponymously affiliated with Hampton hump and Hampton line
Biography Born Kincardine, Canada 1984 – Graduated with MD from the University of Ottawa 1989 – Achieved FRCP Internal Medicine Fellowship from the University of Ottawa 1991 – Achieved FRCP specialisation in haematology at McMaster University 1994 – MSc in clinic epidemiology from McMaster University 2009 – Chair/Chief of the Department of Medicine at The […]
Thomas Fitz-Hugh, Jr (1894 – 1963) was an American Surgeon eponymously affiliated with Fitz-Hugh Curtis syndrome (1930, 1934)
The eponym ‘Wegener Granulomatosis’ has been replaced with the term ‘Granulomatosis with polyangiitis (GPA)’. This transition was in part to achieve nomenclature symmetry with Microscopic Polyangiitis (MPA) and Eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss); and to remove any historical association with Friedrich Wegener following revelations of his association with the Nazi Party in World War II
Emanuel Libman (1872 – 1946) was an American physician. 1924 – Along with his student Benjamin Sacks, defined atypical verrucous valvular lesions in patients with SLE (Libman–Sacks endocarditis)