John Snow (1813-1858) was one of the first anaesthetists – he even chloroformed Queen Victoria! – but today he is famous for his investigation of the 1854 Broad Street cholera outbreak in Soho, London. By mapping the cases of cholera…
Lincoln sign refers to forceful popliteal artery pulsation secondary to aortic regurgitation; exaggerated when the patient sits with legs crossed; and deemed positive if the elevated foot bobs up and down with each systolic contraction.
Guillain-Barré syndrome is the most common and severe acute inflammatory paralytic neuropathy. The classical description of GBS involves rapidly progressive bilateral weakness, usually starting in the distal lower extremities and ascending proximally.
Sir William Osler was a man of not inconsiderable talent. A pathologist and clinician. A professor successively at McGill University, the University of Pennsylvania, Johns Hopkins University and Oxford University. Historian and bibliographer of medicine. A naturalist, microscopist, proponent of…
Alfred Russel Wallace did not knowingly study infectious diseases or their microbial causes, but he did travel extensively and repeatedly put himself in the biological line of fire, as evidenced in his many writings.
Fleming’s role in the discovery and subsequent development of penicillin is well-known parable of the importance of serendipity in medical research. Fewer people know anything about the Scots bacteriologist’s earlier discovery of lysosyme or his work on the bacteriology of traumatic wound infection.
Anton syndrome: Visual anosognosia or Anton-Babinski syndrome is a rare neurological condition related to cortical blindness. The patients deny their blindness and affirm adamantly that they are capable of seeing.
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