eponym LITFL 340
Jules Falret

Jules Philippe Falret (1824 - 1902) was a French psychiatrist. 1877, along with Ernest-Charles Lasègue (1816-1883) first described the concept of Folie à deux, initially termed Lasègue-Falret syndrome.

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ECG Case 077

78 yr old male presents with a 2 day history of lethargy and dizziness. Describe and interpret this ECG. LITFL Top 100 ECG

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Colchicine toxicity

Colchicine toxicity is rare but any intention overdose with colchicine is potentially lethal. Although resuscitation is a priority as with all toxicities, colchicine requires urgent decontamination due to the limited therapies we have once toxic serum levels develop.

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Quinine toxicity

Quinine causes cinchonism (nausea, vomiting and tinnitus) in overdose but also blindness which is delayed and sometimes not noticed until the morning after the acute toxicity has resolved. Think of it as aspirin (the salicylism) that causes blindness.

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Digoxin poisoning

Acute digoxin poisoning manifests with vomiting, hyperkalaemia and brady-tachyarrhythmias potentially leading to death, whereas chronic digoxin toxicity is far more insidious, still with gastrointestinal symptoms but in addition bradycardia and automaticity on the ECG.

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NSAIDs toxicity

NSAIDs are generally benign in overdose unless a large amount is ingested which would take some effort. As 66% of NSAID overdoses are with ibuprofen we will use this as an example.

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Sulfonylurea toxicity

Hypoglycaemia can occur at therapeutic doses especially in those who develop renal impairment. In overdose these drugs cause a profound and prolonged hypoglycaemia, usually apparent within 8 hours post ingestion of a standard preparation.

CICM Exam Library 340
CICM SAQ 2011.2 Q2

Define cachexia. List the factors that may predispose to cachexia AND the consequences of cachexia in a ventilated patient with sepsis and multi-organ dysfunction syndrome.

CICM Exam Library 340
CICM SAQ 2012.1 Q26

In patients suffering from major burns, outline the possible physiologic derangements and their underlying mechanisms that could contribute to problems of oxygenation and ventilation.